ID C3YTK7_BRAFL Unreviewed; 1747 AA.
AC C3YTK7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=BRAFLDRAFT_66631 {ECO:0000313|EMBL:EEN56134.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN56134.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN56134.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN56134.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG666552; EEN56134.1; -; Genomic_DNA.
DR RefSeq; XP_002600122.1; XM_002600076.1.
DR STRING; 7739.C3YTK7; -.
DR eggNOG; KOG0059; Eukaryota.
DR InParanoid; C3YTK7; -.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF225; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 753..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 796..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 830..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 859..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1491..1513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1519..1540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1038..1269
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 396..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1376..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1747 AA; 195648 MW; CBAF06E099822D51 CRC64;
MGFLHQLRLL LWKNFTLKKR SPWVAAFELF IPLVLFFILM AIRQKKPARP HGESYFAAQP
LPSSGVLPVM QALCPGGHRD SYGFPRYDKS TAYQFLERLS NSVQQNALFD EDSDVRQKFY
EILHNYESLV NDPNSLEQRF AQAKDFSLGS VLTDKSEFQK VLMNNLSLSQ DAADYIINTP
IHIQQLYALL FGSPTRNLHN ATDQVLKPKH IWSILQGKLN SLKDGLVYQT LTNPQKLSTK
EGLLALLGQS LGLGTLGEKA EEKVLQPPQQ MVKSLESVLL TPDHLQYLVC NSSAGQIITQ
QQGQEGSMAE VHQALCNTTH TKAKFTALAE GLKAQLNQKA VVDQLGLDQM DIVENQEKME
SLMEALEEFA IFQSGLHDLS DIASVFPSYT CSGITGEEGE APTDPASQAV TAGTDGNSTV
TEPDSPTSQV HHVHNKLSGF IRIWTSLQPT ICGVNKTMTE EALEAGDLRS MGYNKKERRD
LGLLLHLLTS NPKILYSPNG TWADSMTFPN GTEIDKVIKK VAEPFTFISN VTFIADQWLN
RSRELRHFIQ ENSTQQDIQW LRQLKDAYAA NPQLLNMTTN PVIRRFVQSP NVIPNVTTVL
KQLENIDNLA CGWIKLVSNF NLSIFMPFPN EEALVNYTLH QAQKDNVTVF ASVVFNVTNT
TGQLPAHMVF KIRQNASFTQ KTTQIRRKYW RPNPNHGHEL YYQFGFIWIQ DMIERALINV
VVGHDVVEPG SYVHEFPYPC FMADDFLFMI EHMMPLCMTI SWVYTVAMLV QNIVYEKEQR
LKEVMKMMGL NNAVHWVAWF ITSFLQMSLT GTFLMLILQY SQILTYSNPW ITFLFIELYI
VATISFSFFV SVLYSKAKVA AACGGIIYFL SYVPYMYVAI REEVANDKIT AVEKSIACLM
STTAFGLGAK YFALYEESGT GIQWDNFLQS PVEGDAFNLC RVMVMLVVDS FVYCLLTWYI
EAVHPGSYGL PRPWYFPFQK SYWFGHGRQE TLDCHMPCSR GTNYSLALSE EDGACAAEDT
GEEQVSFEEE PTHLPMGVCI HNLVKVYKTG NKLAVNKLAL NLYEGQITSF LGHNGAGKTT
TMSILTGLFP PTAGSATIYG HDIRTDMLEI RKSLGMCPQH NVLFDKLTVE EHVWFYARLK
GMQSADIEKD LQQLIGDVGL QHKRKDPVSS LSGGMKRKLS VAIAFVGGSR TVILDEPTAG
VDPYARRAIW DFLVNYKRGR TILLSTHHMD EADILGDRIA IISNGQLRAC GTSLFLKSTF
GDGYRLTVVK RPVDREEQGS GEPDLNSSSL SNGSIITRCV EQKVSKFIRQ HVAGAVLLSD
TNREISYMLP SEAVKKGCFE KLFSALQSKL DDLDLSSFGL TDTTLEEVFL KVTEATGNDL
PEKEEKDSIP LPTPPEVSSP PVVTPGDPSM VELEMPVRGG VSSGVSAGSY DRLMEDGDNI
SQQSDEPVED PICLDQEGVG SYRLEGCQLA FSQFWGLMIK RFNFSRRNTK ALFSQIVLPA
LFICVAMTVA LLVPDIGDYP PLIVLPALFI CVAMTVALSV PDIGDYPPLV LSPSQYHNYT
SPIGNFIPIS DEKEMQETQL YVDATAQELM QTVHLPSGIG ATCVLKSPFN DTLSMEVIKL
NLTDGAKLPL TDKYFDETCR QSFVHGVRLD NYVPKPPTPA PPPKSLHQKQ NIHYSTSFDP
NPNHTVHENL PVPQCQCMKD NTGFLCTPDP YPPHRFKVIT GDILLDVTGR NTSLWYLNTN
DLYRLHR
//
