ID   C3Z3J4_BRAFL            Unreviewed;      1120 AA.
AC   C3Z3J4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   RecName: Full=Hermansky-Pudlak syndrome 3 protein homolog {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BRAFLDRAFT_120515 {ECO:0000313|EMBL:EEN52758.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN52758.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN52758.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN52758.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666577; EEN52758.1; -; Genomic_DNA.
DR   RefSeq; XP_002596746.1; XM_002596700.1.
DR   AlphaFoldDB; C3Z3J4; -.
DR   STRING; 7739.C3Z3J4; -.
DR   eggNOG; ENOG502QRQB; Eukaryota.
DR   InParanoid; C3Z3J4; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0006996; P:organelle organization; IBA:GO_Central.
DR   InterPro; IPR017216; HPS3.
DR   InterPro; IPR029438; HPS3_C.
DR   InterPro; IPR029437; HPS3_N.
DR   PANTHER; PTHR28633; HERMANSKY-PUDLAK SYNDROME 3 PROTEIN; 1.
DR   PANTHER; PTHR28633:SF1; HERMANSKY-PUDLAK SYNDROME 3 PROTEIN; 1.
DR   Pfam; PF14763; HPS3_C; 2.
DR   Pfam; PF14761; HPS3_N; 2.
PE   4: Predicted;
FT   DOMAIN          4..254
FT                   /note="BLOC-2 complex member HPS3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14761"
FT   DOMAIN          278..533
FT                   /note="BLOC-2 complex member HPS3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14761"
FT   DOMAIN          552..904
FT                   /note="BLOC-2 complex member HPS3 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14763"
FT   DOMAIN          959..1106
FT                   /note="BLOC-2 complex member HPS3 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14763"
FT   REGION          216..240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1120 AA;  124053 MW;  DE980DEABCE2BCED CRC64;
     MVRVLSCHHF TSQEVFSTKQ EPEVIYGSGD KLFIATVHNV VEVYQVNTKE CRHLLGFMTV
     SAIDQLVYSE CGKYVATVEV KSSKQRLYFN WEGSDVTQPV RARIAGVPAS NSQPENTGKQ
     LEVVELPLRK SATCIQCCAV TGNLAIGIGS VMSLYRLCSK TVQLTETTYT DLDHLLDIHI
     GFNLAEIALC ENYVGGISAD EVRVLQVHFK NEVDEDTTNP KELAGEVISR STTPTDQGAD
     QDDVIVEDED FVLWSFEEHN IPVDSVHVEL PSGTSPLPRR SVSPRLQTNT ISLRTISSER
     PYVEKSSNPT EVLGPVDCVQ GRPITVEWAG LYSVGISIKG MNAQLSTTTL LYRRFAPGDT
     AYTTVDGALH SLQFLPTYSK DGADKSEKSR RHRVSVLPAE GRCSPLHPNP QEGTLHGLCC
     FFTGPRQGFL YDIFDGANLL ASYPYTADTS KVVAGDSLLH AVTRNGLETY TLRKFAAAVH
     RMEDIDNIHN TCPHPNMDIC LIGMRPFIAI QDISVCTSHV LLLSKVESPR TQRVAGQSHW
     SLYALQNASV GQLYKDMLDL GLRYQNSSPP AYHQLLCEGH LLLRQALFSQ EAGSRTQQLQ
     DLLCESCGLL GDYHSLPDSQ DWTLALPYYN MSGLKMAAIV QQALHQMQPD REQPGYGRGL
     VHFLDHVLFI GDEPLETDKS TSNIVLEAYS QLEPESLSKV IIKSRLRLFD DQKAVSMLRK
     IKRGVSGSGG RYHPKPLDVL AMAVLKLRLC EPEQAQIVLS TVTEPQLVQV LVSEHQLLRT
     ESTQLSHLSQ LLRRHQPQVL IAALVALQGR GVIAFETALQ LLRGSEGEIH QNTHIRDYLE
     GILQACHSQP AGQKVGTMLC DIYIQRLVEW KPPTSRPMPV PGHVHIPRGG GCFGVRYTWL
     DHLPPFKGVG SAKQPCQWVQ LRVSPPRGSP MQLPATVTPI QVSKASPSVG EEVCTCCCCN
     EDLLKLQSLL CSGNVSTDIS QHVLQAVTED MKGFLAVKLL CLAKMEPEKA VELMIDSHPS
     VLVSFGETVF PESQERWIDV LHLLLQMFED EDSLPDDRHE SLTGALQGVL SCLASLMEPQ
     AFINLLPSHG TVDFFLPYIQ QCLRKHRAGE MRNRVASGQV
//