ID C3Z6W2_BRAFL Unreviewed; 430 AA.
AC C3Z6W2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 72.
DE RecName: Full=TOM1-like protein 2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_259929 {ECO:0000313|EMBL:EEN51558.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN51558.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN51558.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN51558.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR EMBL; GG666590; EEN51558.1; -; Genomic_DNA.
DR RefSeq; XP_002595546.1; XM_002595500.1.
DR AlphaFoldDB; C3Z6W2; -.
DR STRING; 7739.C3Z6W2; -.
DR eggNOG; KOG1087; Eukaryota.
DR InParanoid; C3Z6W2; -.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR CDD; cd03565; VHS_Tom1_like; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF137; GH05942P; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 20..151
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 229..317
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 181..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 430
FT /evidence="ECO:0000313|EMBL:EEN51558.1"
SQ SEQUENCE 430 AA; 47328 MW; 142E63AB95522417 CRC64;
MSFFGGNPFS SQVGQQIEQA TDATLGNENW AMMMEICDII NETDEGPKDA LKAIKRRLQT
KGNHKVLMLT LTVLETCVKN CGHRFHVLVA NKDFVNEMVK IIQPKNNPST TLQERVLSLI
QTMSDAFRNY PDLQGVVQVH EELRSKGVEF PMTDLDNLAP IHTPERSVPP ELDPAIARTR
PASVTAAPAQ RPPSQPQQQP AQQQQPQQNP PGSPGAIGAL QGPINPTPEQ LGKLRSELDV
VEGNTKVMSE MLTEMTPGQE DPADLELLHE LNRTCHAMQQ RIVELIDKVA NEEVTGELLR
INDDLNNVFL RFERFERYRT GKTGQPSTTA PATDTLIDLG PAVSPGGPPP LQPTAAGLQQ
QLAGLSKCGV LTTGLPPGPV LGRKFACWDR KEFHPIPQNT AGRDDDEFDM FAQTRGKSME
ESRRGLVFSS
//
