ID   C3Z9F1_BRAFL            Unreviewed;       697 AA.
AC   C3Z9F1;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   RecName: Full=MACPF domain-containing protein {ECO:0000259|SMART:SM00457};
GN   ORFNames=BRAFLDRAFT_124451 {ECO:0000313|EMBL:EEN50880.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN50880.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN50880.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN50880.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
CC   -!- SIMILARITY: Belongs to the BRINP family.
CC       {ECO:0000256|ARBA:ARBA00010360}.
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DR   EMBL; GG666599; EEN50880.1; -; Genomic_DNA.
DR   RefSeq; XP_002594869.1; XM_002594823.1.
DR   AlphaFoldDB; C3Z9F1; -.
DR   STRING; 7739.C3Z9F1; -.
DR   eggNOG; ENOG502QT9H; Eukaryota.
DR   InParanoid; C3Z9F1; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IBA:GO_Central.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:InterPro.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR   InterPro; IPR033237; BRINP.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR15564; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15564:SF3; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF19052; BRINP; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022810};
KW   Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..697
FT                   /note="MACPF domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002936128"
FT   DOMAIN          46..214
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|SMART:SM00457"
SQ   SEQUENCE   697 AA;  79538 MW;  3E025C10592A8B1C CRC64;
     MKQWVLKRLL AGIVVATLLG TLPSGARGEP DRGPLADSPE LLRYRDQALQ GFRVRVKASR
     NPEEDSIADL DPGFIAVVLS LGERPSREQL IGTLIQPYGT HYVLSGAMGG EETVTVYMNQ
     TDWAVEREVR SLVGSYFADK DGVIEELRDL QKRVSTFRIH TSSTGPISCG SEDDTREAVL
     LSDTNARLKL RGLQDLLPRY LRESFVKAAL SYIYCDGTGE WTCKDGECRC ECDDSAPDCA
     CSADVINRLV SRLEHLHTQF KDDDSRFEQT DGFQRFVGRL PIDQYLDLDA ILERWRRSRM
     VTSSYRVHVA RMKKLLLRID DVMTEIRQRV VYCTWEPELK VKPSPRSQRQ WQAIAQARLY
     CSHGRHPGTF DQQQRACACV DDDTCGSVLP CVIGRAGRCR SCNPADNFAT CGSCNDGYEL
     LDGACRIVLS SNQLGGKLIQ LESYEMPRDE DMCKEKSSIE FYFRSKTAPF QEWFSPTNNS
     LTISLKLRTE NLPPDNIVIL TGVRTKFCFF PFIPNDMEIY AKINPLTENH RDSYRLPQWE
     NSHPKWTTIP YTTPLRYTTS DTDIRCLQMS LCLGQRHKVL TEATHLKLKN LKTDNVEGPL
     RMRIEDVSLF GYRASFNTTA IKESLRNAQA DEIFQKKIGV FFTDIKDKVE RLSPLKDNDI
     LSDLLLKRVG LEVTEVRTIE KLIEDTMKNL EEFREFI
//