ID C3ZBV0_BRAFL Unreviewed; 1209 AA.
AC C3ZBV0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Zinc finger protein ZFAT-like isoform X1 {ECO:0000313|RefSeq:XP_035680255.1};
GN Name=LOC118418450 {ECO:0000313|RefSeq:XP_035680255.1};
GN ORFNames=BRAFLDRAFT_65180 {ECO:0000313|EMBL:EEN50337.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN50337.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN50337.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN50337.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
RN [2] {ECO:0000313|RefSeq:XP_035680255.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035680255.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035680255.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GG666603; EEN50337.1; -; Genomic_DNA.
DR RefSeq; XP_002594326.1; XM_002594280.1.
DR RefSeq; XP_035680255.1; XM_035824362.1.
DR KEGG; bfo:118418450; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; C3ZBV0; -.
DR OMA; HIWAHEX; -.
DR OrthoDB; 3085502at2759; -.
DR Proteomes; UP000001554; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24403:SF67; ENHANCER OF VARIEGATION 3-9-RELATED; 1.
DR PANTHER; PTHR24403; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00355; ZnF_C2H2; 20.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 15.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001554};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 4..31
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 339..366
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 367..394
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 394..422
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 422..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 473..500
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 527..555
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 735..762
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 763..787
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 824..846
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 874..902
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 903..930
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 931..954
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 964..991
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1056..1084
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 24..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..689
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1209 AA; 135955 MW; 6AC7A8CAF363B2DC CRC64;
MDTLTCGLCL RQFGEISDFL DHKKSHADPD APAATSSSAD PGASTCPMEE PPAEPVPVPD
HVEATSSTCI WTCKLCNLFA LSKAELHSHL KSEHADTVPD GDTESFISQL MPLSNMPTSP
QKMTLLLEGH EEETATQPGE ALFSNLPDVK VKTMNDSTIV VPPKKKRGRP RKKPVDENLE
LRLDEEKGTT HDKQRQAILS SDGKLVCDKC NRMFARERQY SRHRCMAEET RDEDEMKAAE
LEEMRAKRKK VAGASTSQLA AREHNYGAVG STQGRAAAAG TAGNQADAEG GVPELGEMGE
DVQTVVQAEG ITHTIQQSLN STAALKPPYL FSRSSLTVFS CEFCSKVFKF RNGLVNHLRV
HTKEKPFKCD RCDYACAVKT NLKTHMRKHT GERFHCQQCD YSSINKGHLK DHIATKHKGE
RHPCEMCSST YTTVRALVKH FREKHDPEAN SDSKEIFDKL KLQTRDGVRD LIYICDLCNR
KFKTRLDKER HVVLHQGMKP FPCGLCEYST NRQANLDLHI RKHKFIYNCC ACEEHFLSSI
PLTAHLQEKH VSEERSFDEL FAKSLEGSKF LFEFGNDVKA FDFDGYQTIE VTPEGHPIHG
QEGEGQQGAA ELLLSHMAQE QQQETVQEQQ AGQKQQKEAA QVQKASTQEQ QDSVQEQQES
DSKKKAEEDQ DETTEKPSGT DSADSESKPE EGESTEDVED QDDGKTVFDT LMEKLEYRKM
SLDVYNKLKV LYGDMECRYC GRFFYYDKTL AQHERTHTGE RPFACNECPY ASATKEGLKR
HIQGSHSKVL IKCEQCEFST NNKYTLWRHT KKEHAPVENL RDSYTCPACS ETFTKERAIK
VHIKKHHPAM TLEEISLVLG KRAQLKSAMG QRAFKCPYCG KLFRKKEPDL RKHIWAHEGI
KPFKCGLCTF ACRSKSNLKA HMLRHTKEKN HLCEECGKKF KTKQSLKFHS QQYHNQGGNE
LKRYYCQICD YSGIQIAHLR RHMEQHSGQK VLKCPLCPYS CNITGAMKRH FNKKHPGKAY
EQVVGSLVKT DLDSPTQVTC SATGTDQVTE MHVEMLKCPE CDFVFGNRWD LNKHLQKRHE
AKVVNLMEVD AALGATHHVV EVTESGDGQV IYTDATGVLQ TEGGDTSAAV NILQQIMDIT
QQEAASTHVV TTTTANVSES QAMVALAPDA VVVEQAGGDG MQHIVSSGEG ERPQGQEYIV
YLTQSTEAL
//
