ID C3ZG40_BRAFL Unreviewed; 503 AA.
AC C3ZG40;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=TNF receptor-associated factor 2-like {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_68995 {ECO:0000313|EMBL:EEN48515.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN48515.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN48515.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN48515.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GG666616; EEN48515.1; -; Genomic_DNA.
DR RefSeq; XP_002592504.1; XM_002592458.1.
DR AlphaFoldDB; C3ZG40; -.
DR STRING; 7739.C3ZG40; -.
DR eggNOG; KOG0297; Eukaryota.
DR InParanoid; C3ZG40; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0070534; P:protein K63-linked ubiquitination; IBA:GO_Central.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0043122; P:regulation of canonical NF-kappaB signal transduction; IBA:GO_Central.
DR GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IBA:GO_Central.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR012227; TNF_rcpt-assoc_TRAF_met.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR032070; TRAF_BIRC3-bd.
DR InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131:SF138; MATH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF16673; TRAF_BIRC3_bd; 1.
DR Pfam; PF02176; zf-TRAF; 1.
DR PIRSF; PIRSF015614; TRAF; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 3.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS50145; ZF_TRAF; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..503
FT /note="TNF receptor-associated factor 2-like"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002936743"
FT DOMAIN 56..102
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 112..167
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 121..148
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 351..497
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT ZN_FING 56..102
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 112..167
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT COILED 214..327
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 503 AA; 57321 MW; 7125F93C4186AFD7 CRC64;
MMLLLMIIGL ISIATVTRLQ VFPDKAIERE IKSIPVLCNN DDDGCKWEGL LKDLKAHLDE
CEYEKIACIH KNCGEKIPRR DLSKHLNENC GFRSAACQFC KESHPFKDIA NHQESCPMAP
ARCKWCGKKG LTRSQLQDHQ HPQTGDCPNM KLPCHFEPVG CTEKLERKQH GDHQKKTITA
HLNMVLAMLL QLATNVEGLR DEDVEARENM RAAIPRLDKN LNDQITKVSE LERKLSSYQS
EGATGSGSSG LKALENRIEQ IRAKVEDLIK KLAAWEPRVG TFEGIVAVLN REIEKCSSQM
EAYERQRRQD REIIETLERK VRSLERIIAL KDVALAEQDL RIQTLELTSY DGILTWKIAD
FTRKRHDAIT GKTASFYSPC FFTSRTGYKM CARIYLNGDG MGKGTHVSLF FVVMRGHYDG
LLRWPFRQKV TFMLLDQNNR EHVIDAFRPD PTSSSFQRPT SDMNIASGCP LFVPLSQLDS
SSHAYVRDDT MYLRVIVDTS DLN
//
