ID C3ZMG4_BRAFL Unreviewed; 238 AA.
AC C3ZMG4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Ribosome assembly factor mrt4 {ECO:0000256|RuleBase:RU364039};
GN ORFNames=BRAFLDRAFT_254316 {ECO:0000313|EMBL:EEN46259.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN46259.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN46259.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN46259.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC of the ribosomal protein P0, it binds pre-60S subunits at an early
CC stage of assembly in the nucleolus, and is replaced by P0 in
CC cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC {ECO:0000256|ARBA:ARBA00004046, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC {ECO:0000256|RuleBase:RU364039}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU364039}.
CC Nucleus, nucleolus {ECO:0000256|RuleBase:RU364039}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000256|ARBA:ARBA00008889, ECO:0000256|RuleBase:RU364039}.
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DR EMBL; GG666645; EEN46259.1; -; Genomic_DNA.
DR RefSeq; XP_002590248.1; XM_002590202.1.
DR AlphaFoldDB; C3ZMG4; -.
DR STRING; 7739.C3ZMG4; -.
DR eggNOG; KOG0816; Eukaryota.
DR InParanoid; C3ZMG4; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR CDD; cd05796; Ribosomal_P0_like; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR InterPro; IPR033867; Mrt4.
DR InterPro; IPR001790; Ribosomal_uL10.
DR InterPro; IPR040637; Ribosomal_uL10-like_insert.
DR InterPro; IPR043164; Ribosomal_uL10-like_insert_sf.
DR InterPro; IPR043141; Ribosomal_uL10-like_sf.
DR PANTHER; PTHR45841:SF1; MRNA TURNOVER PROTEIN 4 HOMOLOG; 1.
DR PANTHER; PTHR45841; MRNA TURNOVER PROTEIN 4 MRTO4; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU364039};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364039};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU364039}.
FT DOMAIN 125..194
FT /note="Large ribosomal subunit protein uL10-like insertion"
FT /evidence="ECO:0000259|Pfam:PF17777"
FT REGION 219..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 238 AA; 27541 MW; 5923747FD905777F CRC64;
MPKSKRDKKI SLTSTRKKGL ELKRNLVDQI RECVDQYARI FTFSVENMRN SKLKEVRNVW
KHSRFFFGKN KVMSVALGRG AEDKYRENLH RVSQRLRGQT GMFFTNKTKE EVVEWFSQYQ
LKDFARSGNT AVQTVVLFEG PLPQFSHSME PQLRQLGLPT KLERGEITLI SDHTVCTAGD
VLTPEQARIL KLLDTPMVNF HITLDSVWSN DGTFELLERG DKPAEDEGIE EEEEDEND
//
