ID C3ZQK6_BRAFL Unreviewed; 378 AA.
AC C3ZQK6;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Carbohydrate sulfotransferase {ECO:0000256|RuleBase:RU364020};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU364020};
GN ORFNames=BRAFLDRAFT_74591 {ECO:0000313|EMBL:EEN45262.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN45262.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN45262.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN45262.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323, ECO:0000256|RuleBase:RU364020}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323,
CC ECO:0000256|RuleBase:RU364020}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006339, ECO:0000256|RuleBase:RU364020}.
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DR EMBL; GG666661; EEN45262.1; -; Genomic_DNA.
DR RefSeq; XP_002589251.1; XM_002589205.1.
DR AlphaFoldDB; C3ZQK6; -.
DR eggNOG; KOG4651; Eukaryota.
DR InParanoid; C3ZQK6; -.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR InterPro; IPR018011; Carb_sulfotrans_8-10.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12137; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12137:SF33; CARBOHYDRATE SULFOTRANSFERASE 14; 1.
DR Pfam; PF03567; Sulfotransfer_2; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364020};
KW Glycoprotein {ECO:0000256|RuleBase:RU364020};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364020};
KW Signal-anchor {ECO:0000256|RuleBase:RU364020};
KW Transferase {ECO:0000256|RuleBase:RU364020};
KW Transmembrane {ECO:0000256|RuleBase:RU364020}.
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 44162 MW; 6A1CF7228988C149 CRC64;
MGKEKNAEKC TGPMPEPEPK TKKYRTRSGN AKTKPWNTPT KSIQEFEQFT EDHTNTSKTK
APLSEVLKSL IVIDKYKVLY CRTGKTGSWT TMQLLYNLEL GTNMSRREVR KFAREKRLPI
LSDFSEEDIW LRLATYKKFL VARNPLERLA SVWSGFFVTY PVYGWNEKYS SMMETICPEM
KTKKITCNKT IEIKWKGNQT HQLVPFKAFA KAVAASANRT EFQNQHWKPI SEICSPCQIT
CNKTIEIKWK GNQTHQLVPF KAFAKAVAAS ANRTEFQNQH WKPISEICSP CQIHYDFVGH
MENLAEDLNT FFRHDVGVVG RDNIFPQRKP RIGDQMLHKD FQKVSIEDMN NLYERHNYYK
DPSSEEKKDF LQTIHFIF
//
