ID C3ZUE9_BRAFL Unreviewed; 379 AA.
AC C3ZUE9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEN43877.1};
GN ORFNames=BRAFLDRAFT_94120 {ECO:0000313|EMBL:EEN43877.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN43877.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN43877.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN43877.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
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DR EMBL; GG666682; EEN43877.1; -; Genomic_DNA.
DR RefSeq; XP_002587866.1; XM_002587820.1.
DR AlphaFoldDB; C3ZUE9; -.
DR eggNOG; KOG4294; Eukaryota.
DR InParanoid; C3ZUE9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015280; F:ligand-gated sodium channel activity; IBA:GO_Central.
DR GO; GO:0035725; P:sodium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR Pfam; PF00858; ASC; 1.
DR PRINTS; PR01078; AMINACHANNEL.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 379 AA; 42738 MW; 1EE86A3CD509AA63 CRC64;
MSPQEEKESP EKEFAGNTTL HGLNRIVIAP SGYFRVLWVF AILASYSGFS YMLSSMIMDY
FSYDTITDTK LQFTDGLPFP AVTICNMNMF DAGKLTLVET SYLSPYLYRT QLDIPTLLAI
GFNPDDTINS TIGNITLQDI VFQNGFDINP DRMSLCFWKN EACTYLNFTH SYTSFGNCYT
FNSDKSNTLW QTMEGHGNGL MVFVDVRADQ YTESYFSGGN SEIGLKLLVH DQDEPPMMET
QGIALAPGSH AFIGVKRTVY ENHVPPWGVC EDRQLEYYDT YTMNGCYLEC RSKHVIANCS
CRPFSLPGKA PLCDPGNIGG MMGLFIGASL LTLLEVWEYL WQRLKGFLGK STIRHPRVAE
VQAEPDNKAE SMHNATFYK
//
