ID   C3ZWZ0_BRAFL            Unreviewed;        99 AA.
AC   C3ZWZ0;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
DE   Flags: Fragment;
GN   ORFNames=BRAFLDRAFT_244348 {ECO:0000313|EMBL:EEN42952.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN42952.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN42952.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN42952.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666705; EEN42952.1; -; Genomic_DNA.
DR   RefSeq; XP_002586941.1; XM_002586895.1.
DR   AlphaFoldDB; C3ZWZ0; -.
DR   STRING; 7739.C3ZWZ0; -.
DR   eggNOG; KOG4641; Eukaryota.
DR   InParanoid; C3ZWZ0; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017241; Toll-like_receptor.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR24365:SF548; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
FT   DOMAIN          5..99
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEN42952.1"
FT   NON_TER         99
FT                   /evidence="ECO:0000313|EMBL:EEN42952.1"
SQ   SEQUENCE   99 AA;  11709 MW;  C70699390896B3FA CRC64;
     LDQHEKHHVF FCYSNANAPW VKDMIDKLES DELGFKCCFH ERDFIPGMSI IENIVRSIQK
     TVFVLSRDFV ASRWCNFERQ MVMGANLREE NKKVIPVML
//