ID C4F7X6_9ACTN Unreviewed; 546 AA.
AC C4F7X6;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EEP45094.1};
GN ORFNames=COLINT_02141 {ECO:0000313|EMBL:EEP45094.1};
OS Collinsella intestinalis DSM 13280.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC Coriobacteriaceae; Collinsella.
OX NCBI_TaxID=521003 {ECO:0000313|EMBL:EEP45094.1, ECO:0000313|Proteomes:UP000003295};
RN [1] {ECO:0000313|EMBL:EEP45094.1, ECO:0000313|Proteomes:UP000003295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13280 {ECO:0000313|EMBL:EEP45094.1,
RC ECO:0000313|Proteomes:UP000003295};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP45094.1}.
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DR EMBL; ABXH02000003; EEP45094.1; -; Genomic_DNA.
DR AlphaFoldDB; C4F7X6; -.
DR STRING; 521003.COLINT_02141; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_5_11; -.
DR Proteomes; UP000003295; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 42..188
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 232..534
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 546 AA; 58712 MW; 46BD3E96F7145AB4 CRC64;
MLAGGFLAAS AIVLARLSEI QIFNTDWYRE QANARRVSSQ TLYAKRGTIY DRNGTVLVSS
IECKNVYLNP SLIKKKQRRR AIDALVDVLG MDEDVVEDLV DREGTFVYVK RQVDEEDAEL
LAKKGIAGIE FEPAIKRVYP NGSLASQVLG VVNVDNEGIT GLEKQYNEVL TGVNGSLMRE
RARDGSFIAG GAYEKVPAQD GMDIVLGIDA NVQRVAEDAI AEAVERVGAT YGSIIVTDPT
TGEIIAACSY PTYDPTDLAS ASNASMNLRV VTDVYEPGSV FKTFVSAAAI EHKGLTPDTT
FDVPAEVLVG SDIVRDVDKR GAAMTMSLRE ILRRSSNTGM VLVGEKLGAD AFSEYVIDGF
QFGKSTGIDF PGESLGIIKK RSEYDGASLG SMSFGQSLAV EPVQMVRAMS AIANKGVMTT
PHFLKTRAGE EVDWTDGEHR VLSEETAASV ADMMLTVVDE GTGMDAQMPG YEVSGKTGTA
ERAGKDGGYE EGNNMASFMG FVSTKDPRVL CYVTLDGTAA MSYAATPVFR KVMEEALPAL
GIKPTR
//
