ID C4GAW7_9FIRM Unreviewed; 1020 AA.
AC C4GAW7;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Type III restriction enzyme, res subunit {ECO:0000313|EMBL:EEP28260.1};
GN ORFNames=GCWU000342_01068 {ECO:0000313|EMBL:EEP28260.1};
OS Shuttleworthia satelles DSM 14600.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Shuttleworthia.
OX NCBI_TaxID=626523 {ECO:0000313|EMBL:EEP28260.1, ECO:0000313|Proteomes:UP000003494};
RN [1] {ECO:0000313|EMBL:EEP28260.1, ECO:0000313|Proteomes:UP000003494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14600 {ECO:0000313|EMBL:EEP28260.1,
RC ECO:0000313|Proteomes:UP000003494};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP28260.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACIP02000002; EEP28260.1; -; Genomic_DNA.
DR AlphaFoldDB; C4GAW7; -.
DR STRING; 626523.GCWU000342_01068; -.
DR eggNOG; COG3587; Bacteria.
DR HOGENOM; CLU_011799_0_0_9; -.
DR Proteomes; UP000003494; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR045572; RE_endonuc_C.
DR PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR Pfam; PF19778; RE_endonuc; 1.
DR Pfam; PF04851; ResIII; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003494}.
FT DOMAIN 81..258
FT /note="Helicase/UvrB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04851"
FT DOMAIN 903..1010
FT /note="Type III restriction enzyme C-terminal endonuclease"
FT /evidence="ECO:0000259|Pfam:PF19778"
SQ SEQUENCE 1020 AA; 115973 MW; 307D1AE24DE21ACE CRC64;
METKTMRLRF KHQKFQADAA KAVVDVFAGQ PYLTPSYMMD RGNGYYQQSL TDEEDFTGWS
NHKIVPELSD RIILENLQKV QRTNQLKPSP KLEGHFNLTI EMETGVGKTY TYIKTMYELN
KHYGWSKFIV VVPSIAIREG VYKSFQVTQE HFAEEYSKKV RFFVYNSAQL TEIDRFASDN
SICAMIINSQ AFNARGKDAR RISMRLDEFR SRRPIDIIAK TNPILIIDEP QSVEGKQTKE
NLKQFNPLLT LRYSATHKSD SIYNMVYRLD AMEAYNKRLV KKIAVKGISE SGSTATESYI
YLENINLSKA APTATIQFDV KGASGTRKVT RTVSEGFNLY DNSGNMEEYK QNFVVSRIDG
RDDSVEFLNG IKIYAGDVIG KVSEDQLRRI QIRETILSHI QRERELFYKG IKVLSLFFID
EVAKYRLYDE AGQGTDGIYA QMFVEEYNDI IGNLQIGIGE DDYIKYLHAI PAEKTHAGYF
SIDKKGKMID SKVGRKQTTT DDVDAYELIM KNKELLLDRD PKRSPVRFIF SHSALREGWD
NPNVFQICTL KQSSSEVRKR QEVGRGLRLC VNQDGERMDT NVLGEDVQNV NVLTVVASES
YDSFAKGLQT EIAEAVADRP RAVTADLFVG KVIEDDKGNE QVVDQDTARA IHFDLIVNGY
IDRKGNLTDK YYADKANNEI KIAEEVADSS ASVIEIIDSI YDGKSMMPEN ARSNNVELHV
DENKLTMPEF KALWAKINAK STYVVDFDTD ELIHKAIQSL DRKLRVSKII FKVETGIMEK
IKSKEELISG VSFLREESVS YGHTITASSN VKYDLIGKFV EETGLTRKAV VQILKGIQPS
VFGQFKDNPE EFIIKAAALI NDEKATAIIE HITYDVMDDH YGTDVFTDPT IKGRLGVNAM
KAKKHLYDHI VYDSSNEQKF ATELDTNTNV AVYVKLPDGF YISTPVGHYN PDWAIAFYEG
TVKHIYFVAE TKGSMNSMQL RLIEESKIHC AREHFKAISN GDVVYDVVDS YQSLLDLVTK
//
