ID C4GCG0_9FIRM Unreviewed; 739 AA.
AC C4GCG0;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN Name=glnA {ECO:0000313|EMBL:EEP27660.1};
GN ORFNames=GCWU000342_01654 {ECO:0000313|EMBL:EEP27660.1};
OS Shuttleworthia satelles DSM 14600.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Shuttleworthia.
OX NCBI_TaxID=626523 {ECO:0000313|EMBL:EEP27660.1, ECO:0000313|Proteomes:UP000003494};
RN [1] {ECO:0000313|EMBL:EEP27660.1, ECO:0000313|Proteomes:UP000003494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14600 {ECO:0000313|EMBL:EEP27660.1,
RC ECO:0000313|Proteomes:UP000003494};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP27660.1}.
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DR EMBL; ACIP02000004; EEP27660.1; -; Genomic_DNA.
DR AlphaFoldDB; C4GCG0; -.
DR STRING; 626523.GCWU000342_01654; -.
DR eggNOG; COG3968; Bacteria.
DR HOGENOM; CLU_024307_0_0_9; -.
DR Proteomes; UP000003494; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:EEP27660.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003494}.
FT DOMAIN 99..193
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 198..629
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
FT COILED 663..690
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 739 AA; 82581 MW; 4E2D414E52A9A739 CRC64;
MAPFTFYDRG MFAERASHCR KKLSPTGGNR MDNKETTYCS VTDIFGENVF NDTVMRERLP
KKTYQKLKQT IREGRDLDIE TADVVAHEMK EWAIEKGATH YTHWFQPLNG VSAEKHDSFI
TAPMSNGKVL MSFSGKELIK GEPDASSFPS GGLRATFEAR GYTAWDCTSN AFVRQDAAGA
TLCIPTAFCA YTGEALDQKT PLLRSMEAIN EQALRLLRLL GNTSSKKVIP SVGAEQEYFL
VDRDNYLKRK DLIYTGRTLF GAMPPKGQEM DDHYFGAIPE RIESFMKDVN EELWKLGVPS
KTQHNEVAPA QHELAPIYGE CNVAVDQNHL VMETLKKVAV RHKLQCLLHE KPFAGVNGSG
KHNNWSLVTD DGINLIDPGK RPHENTLFLL SLACILAAVD KHADLLRESA ADIGNDHRLG
GNEAPPCVIS VFLGDQLADV MEQVLDKGEA THSKKGAKLQ TGVKSIPDFA KDVTDRNRTS
PFAFTGNKFE FRMCGSQDSI GEANVVLNTI VAEQFADVCD ELEKAKDRDA TIQKIIKDLM
TRHQRIVFDG NGYSEEWRKE AARRGLADIR SMVDAIPALA SETTVALFER FHVFTREELN
SRVEIEYDQY AKEINIEAKT MVDVASKSIV PAVIRYSTRL ADSINQVSSA CPEADTSVQS
TILKNTSKLL AKTQKALRAL EKAVADADQQ RGSEKRAQYF HKTVMARMDA LRQPVDELEM
IVDKDLWPMP SYGDLIFEV
//
