ID C4GES3_9NEIS Unreviewed; 775 AA.
AC C4GES3;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein {ECO:0000313|EMBL:EEP68728.1};
GN ORFNames=GCWU000324_00632 {ECO:0000313|EMBL:EEP68728.1};
OS Kingella oralis ATCC 51147.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Kingella.
OX NCBI_TaxID=629741 {ECO:0000313|EMBL:EEP68728.1, ECO:0000313|Proteomes:UP000003009};
RN [1] {ECO:0000313|EMBL:EEP68728.1, ECO:0000313|Proteomes:UP000003009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51147 {ECO:0000313|EMBL:EEP68728.1,
RC ECO:0000313|Proteomes:UP000003009};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004571}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004571}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC {ECO:0000256|ARBA:ARBA00009810, ECO:0000256|RuleBase:RU003357}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP68728.1}.
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DR EMBL; ACJW02000002; EEP68728.1; -; Genomic_DNA.
DR RefSeq; WP_003794179.1; NZ_GG665871.1.
DR AlphaFoldDB; C4GES3; -.
DR STRING; 629741.GCWU000324_00632; -.
DR GeneID; 84907007; -.
DR HOGENOM; CLU_008287_19_0_4; -.
DR OrthoDB; 9764669at2; -.
DR Proteomes; UP000003009; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01347; ligand_gated_channel; 1.
DR Gene3D; 2.40.170.20; TonB-dependent receptor, beta-barrel domain; 1.
DR Gene3D; 2.170.130.10; TonB-dependent receptor, plug domain; 1.
DR InterPro; IPR012910; Plug_dom.
DR InterPro; IPR037066; Plug_dom_sf.
DR InterPro; IPR039426; TonB-dep_rcpt-like.
DR InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR InterPro; IPR010949; TonB_Hb/transfer/lactofer_rcpt.
DR InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR InterPro; IPR010917; TonB_rcpt_CS.
DR NCBIfam; TIGR01786; TonB-hemlactrns; 1.
DR PANTHER; PTHR30069; TONB-DEPENDENT OUTER MEMBRANE RECEPTOR; 1.
DR PANTHER; PTHR30069:SF54; TRANSFERRIN-BINDING PROTEIN A; 1.
DR Pfam; PF07715; Plug; 1.
DR Pfam; PF00593; TonB_dep_Rec; 1.
DR SUPFAM; SSF56935; Porins; 1.
DR PROSITE; PS01156; TONB_DEPENDENT_REC_2; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003357};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EEP68728.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003009};
KW Signal {ECO:0000256|SAM:SignalP};
KW TonB box {ECO:0000256|ARBA:ARBA00023077, ECO:0000256|RuleBase:RU003357};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..775
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002936444"
FT DOMAIN 51..154
FT /note="TonB-dependent receptor plug"
FT /evidence="ECO:0000259|Pfam:PF07715"
FT DOMAIN 251..727
FT /note="TonB-dependent receptor-like beta-barrel"
FT /evidence="ECO:0000259|Pfam:PF00593"
SQ SEQUENCE 775 AA; 88246 MW; C841B4C632F6155B CRC64;
MRNIQPTLKI CLLAVLSAYS AQAVSAPAEQ TLQNIQVSGK RLAKQNTAEH KKREDIDREL
IRDNNDLVRY SPDVGVSQSG TRHSKGFAMR GVEGNRVGVS IDGVSLPDSE ENSLYARYGN
FNNSRMSIDT ELVRGIDVEK GANSFSMGSG ALGGGVNYRT LDAGNLLQDD NRFGGLIRSG
YASKNREWAN TVGLATGNER ADFMLLYSQR RGHETKSSGK GEDTIGSARG IPDPARHKYH
SFLSKFNWQL TDNQRVGVAF NGQQGHNRVN ELSYNLQESS WREADDINYR RNLHLYHEFA
PARYLSLVKT EFDYQKTDLA SVSDKGSYPR DWSKPDFPLD YSKKDLDEVY DRRMKTTFHR
LSLSLDGKPF QWGGTHQLSF KTFVSKRDFK NINSDSYYLD GKVYNVKSTI QHPVQTRQFG
FSLLDSIQWN DRFSNQIGVR YDHTRLNPQA LNETCNACET TIPAPGSFRA WNGFVDTQWR
MNDAWRLNYQ VTTGYRIPTA SEMYFTYKHP AGNWLANPNL KAERSLNQTI TLSGNGRFGK
MDLSAYHTRY KNFIFEQENA PIENGRMQLY QQMVNVDKAR ISGLEFSGSL KLPKGFSLMG
SLGYSKGRLN NGLSQLPLQP IKAVIGLDYE HPEQRWGIFS RLTYMGAKKA KDAKILHHEQ
KETCLAYETE EDWWTGETYT YCSKRHVEAV ESKETFPYLN RSAVVLDVFG YVRPTKNLTL
RAGVYNLTNR RYATWDSFRS INIRSTTGSV DKDGKGLARF YAPGRNYSVS LEYKF
//
