ID C4ICS7_CLOBU Unreviewed; 898 AA.
AC C4ICS7;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=AAA superfamily ATPase with N-receiver domain {ECO:0000313|EMBL:EEP55756.1};
GN ORFNames=CLP_3150 {ECO:0000313|EMBL:EEP55756.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP55756.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP55756.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP55756.1}.
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DR EMBL; ACOM01000002; EEP55756.1; -; Genomic_DNA.
DR AlphaFoldDB; C4ICS7; -.
DR eggNOG; COG1221; Bacteria.
DR eggNOG; COG3933; Bacteria.
DR HOGENOM; CLU_014204_1_0_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR32071:SF38; PSP OPERON TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003081};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 89..323
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 544..679
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 798..898
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 898 AA; 102499 MW; 7F10397B253ABEDD CRC64;
MKNEEKIKMV IATLSSNALK KGEQGITAQD ISEVLGIKRN VISHYLNRMV DDGLVIKTKT
RPVYFLYKEV IDQFNNEQLN QEDDIFSKVI GVNGSLANAV KECKSATLYP RNGLPILLTG
SSGVGKSFMA KLIYEYAKEK KVIKEDAKFI TFNCAEYSDN KELLSSKLFG YVKGAFTGAD
KESKGVIDEA KDGYLFLDEV HRLSPEGQEK LFLLLDKGVF ERIGESGNPR KVNIRLICAT
TEKLDEFLID TFIRRIPIIT NLPSIDERPI DERVELIYRF YKDESDILKN DIVVNSEVMN
NLLFMNKVGN VGALKNAIKY SCASSFRNSH SGEMVIGLDN LPESFINADN IKKVYFDTNF
HIKCGEKISE IVCKKETTII IEQYINMIEE IYEITEKYNE NLIKVDEYRK ILVSKLNNIN
DLIISSDIHE NDNINFKLSL NVVEKALSKL ENNYGIKYYN NSSRIITSAL LLFENAKELN
NPEIINMQKD IINILKNKNF KYNYISVKIL NDIENNREFN LGINGEMYIT LFIYMLTKSK
DINDINGIIV AHGDSTASSI ASVVNKLLGE FIFEPFDMPI DMNPQEVTGI IKKYIKNFSK
SKGTIFLVDM GSLFEIYPSI KDSMDDEVAV INNITTQLAL SVGDMILKEK TIKEIIDTAI
RDTNISYKYF ESKEKKKAII TCCATGIGVA TKIKDIIKSC IEDENIEVLA YDYFKLKNNG
LNDMVFDDYE VELIISTLDL KIKGFDVILL SDCFRKDGEE RLRKAFCKIL KNRSADTLIK
DLIKLLSLQN IISRMIILNP ERVINDVERI INILETELEV KLNSDLRLTL FIHTAIMIER
VVLNRDTKFD DDDEIHISCD TRDLELVQNI LDNELKEYSI KIPAYETAVI VGIIKNRI
//
