ID C4II88_CLOBU Unreviewed; 298 AA.
AC C4II88;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Transcriptional regulator, RpiR family {ECO:0000313|EMBL:EEP53112.1};
GN ORFNames=CLP_2123 {ECO:0000313|EMBL:EEP53112.1};
OS Clostridium butyricum E4 str. BoNT E BL5262.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=632245 {ECO:0000313|EMBL:EEP53112.1, ECO:0000313|Proteomes:UP000003081};
RN [1] {ECO:0000313|EMBL:EEP53112.1, ECO:0000313|Proteomes:UP000003081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E4 str. BoNT E BL5262 {ECO:0000313|Proteomes:UP000003081};
RA Shrivastava S., Brinkac L.B., Brown J.L., Bruce D.B., Detter C.,
RA Green L.D., Munk C.A., Rogers Y.C., Tapia R., Sims D.R., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEP53112.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACOM01000005; EEP53112.1; -; Genomic_DNA.
DR RefSeq; WP_002580018.1; NZ_ACOM01000005.1.
DR AlphaFoldDB; C4II88; -.
DR STRING; 1492.ATN24_09495; -.
DR GeneID; 66381473; -.
DR eggNOG; COG1737; Bacteria.
DR HOGENOM; CLU_055769_1_1_9; -.
DR Proteomes; UP000003081; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF18; RPIR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003081}.
FT DOMAIN 10..86
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 132..270
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 298 AA; 33167 MW; 95898E6B24996C96 CRC64;
MEELNNENSK DLMRLIQGKF IRLSKGQKLI AEYILKNYDK AAFMTAAKLG NAVGVSESTV
VRFAIEVGFS GYPKLQKALQ ELIKNKLTTV QRLELRNDYF SDGDALKGVL KADMENIRAT
LEKINQNTFQ DVVQHIFEAK RIYIIGLRSS TALAEFLGFY LNIILQNVKV VSYGISDVFE
QMINVGEGDL VIGIGFPRYA AKTIDALEFS QDRGAKVVAL TDSLLSPLAT KADYTLIAQS
NMASFVDSLV APLSVINALI IAVGMREKEN ISNVFSNLEL IWKNYNVYSI NNKNVADD
//
