ID C4JDL8_UNCRE Unreviewed; 744 AA.
AC C4JDL8;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Sister chromatid cohesion protein {ECO:0000256|RuleBase:RU364107};
GN ORFNames=UREG_00727 {ECO:0000313|EMBL:EEP75880.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP75880.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364107}.
CC -!- SIMILARITY: Belongs to the SCC2/Nipped-B family.
CC {ECO:0000256|ARBA:ARBA00009252, ECO:0000256|RuleBase:RU364107}.
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DR EMBL; CH476615; EEP75880.1; -; Genomic_DNA.
DR RefSeq; XP_002541213.1; XM_002541167.1.
DR AlphaFoldDB; C4JDL8; -.
DR STRING; 336963.C4JDL8; -.
DR GeneID; 8443673; -.
DR KEGG; ure:UREG_00727; -.
DR VEuPathDB; FungiDB:UREG_00727; -.
DR eggNOG; KOG1020; Eukaryota.
DR HOGENOM; CLU_373473_0_0_1; -.
DR InParanoid; C4JDL8; -.
DR OrthoDB; 1409889at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0061780; P:mitotic cohesin loading; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026003; Cohesin_HEAT.
DR InterPro; IPR024986; Nipped-B_C.
DR InterPro; IPR033031; Scc2/Nipped-B.
DR PANTHER; PTHR21704:SF18; NIPPED-B-LIKE PROTEIN; 1.
DR PANTHER; PTHR21704; NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED; 1.
DR Pfam; PF12765; Cohesin_HEAT; 1.
DR Pfam; PF12830; Nipped-B_C; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU364107};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364107};
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364107}.
FT DOMAIN 432..476
FT /note="Sister chromatid cohesion C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12830"
FT DOMAIN 497..534
FT /note="Sister chromatid cohesion C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12830"
FT REGION 402..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 81250 MW; F4222BF7BDB7AF8B CRC64;
MALILRCATD SSPMVRDSAL SLIAKCMFLK PGLEESCCRA ILACSSDQTV GVRKRCIGLM
KEVYAQTSNQ ELKLAVIEQL LQRVTDHEST VAAQARQALE EMWFSPLHSS FTNPAQRTPQ
SQVSLENLMN LMVGSVKRNE GVIPTFEAFI KHELSPEAKA TSLNFNVCKA VVAAMFDRIV
HDADNTDKST LQSLLQSITL FSKANAKLFT PDQLETLHPY IGHLSNADDL ILFRSVVVIY
RCVLPYLSTS HNTLLKDIQN DLFKSINQAA SAKLDASTDA DALGRVRSYI RIAGCVGKHC
DLESFRSFFA QSFPHMKATS VAGLMVDFIS PFASSKYPPE LRVMALESLG AVCETWPAQY
SAERAREALT SVFEEDSADL QNIVLRGFLA FFSIHEGKSE KLIQSKDTSG DNEGSTRLGG
SLKASENDGA AALIAQHFLQ QMLRAALSKE DSHALTAIEL IASINRQGLI HPKECAGGPG
LLGDKIDFEP RKLDISGTPP EHLLLSRFVC QNLAYFEYAQ VGELLATVTC MERIVGSTGT
TVAHAIETDI FPVKIDSTGE RMEIDGQTSD NVSRPVDPDN LKQLATAATT LSMLWETRTY
LRRLYGVSFH SLPKESKAGA KEATKSLAKV PGTSGDRLWD AMSKNMACLE SVEGMMSICK
EFATLMSIDD ELKIAANDDR DGHDSTADLG DMNQVISASS GPKSGKRRSS VSSGNAPKRP
RQKARGKNAK KRGSPDSEHD GEFD
//
