ID C4JER5_UNCRE Unreviewed; 783 AA.
AC C4JER5;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=SAM and PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=UREG_02225 {ECO:0000313|EMBL:EEP77376.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP77376.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476615; EEP77376.1; -; Genomic_DNA.
DR RefSeq; XP_002542709.1; XM_002542663.1.
DR AlphaFoldDB; C4JER5; -.
DR STRING; 336963.C4JER5; -.
DR GeneID; 8441503; -.
DR KEGG; ure:UREG_02225; -.
DR VEuPathDB; FungiDB:UREG_02225; -.
DR eggNOG; ENOG502SEFA; Eukaryota.
DR HOGENOM; CLU_009306_0_0_1; -.
DR InParanoid; C4JER5; -.
DR OMA; PPDMNYR; -.
DR OrthoDB; 1405875at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR CDD; cd09535; SAM_BOI-like_fungal; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12844:SF45; CNK3_IPCEF1 FUSION PROTEIN-RELATED; 1.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 182..246
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 627..765
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 58..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 86519 MW; D03500284BFD37B2 CRC64;
MEITYQLPQP QMGVRMLQMN TNSITLLPRR SSFNSRPLSE ATEILDTDDE TEYFEFGSPR
RSVESLENDS ATTLSTPDDL PTPSALDTAF KIGLDVNKPV QGPTGPHLFR SSLDASIAGK
SDESEWQFPS SPNPLDGARN STILFNEQIF DSRPQVEEIR PGSALSIARA SPHQDVNDVR
AWTPAQVAEW MYEAGLEDMV VERFIENDIS GTVLLDLQIE DLKELDIQSF GKRHCLMNMI
QNLRSGACTR PNELPSVRMS RSASMRRTGS KETPVQSPIS DRDTSRRRRN RVISEKDIIS
PGESVSIVAI EQLIPKPHKC SKGENCPKYQ KRQRKIARIA KEFPNEFAQV GEDHVSVKLS
SPVKPDDGPR PKSDATPSVV ASSDVLGPSQ LSDLKLNAEN LNGVQPRDPQ ENVRQFLTFQ
HMHSPSNAEY NQPALEMFPP LSPPASSSLP LHMTNQLRSL PKLVIPRSSS ADNAFSPDRT
ITPSLGLQPM GSATATQEMN PFQFGQDVFR QVTPFSEMDV PVTAMPIEPL DRDGSQSVPP
NMRYGTLQPP AIDSIPRPPS VRPDHHRRRP SFAAMAPLTE GRVLPPINNP SDLRTIPLAK
SQAQQVSSPQ SAVEPGQTAT TSSKHPDAAY SGWMKKRKTR LLRHEWHDAH FTLKGTVLAM
QKDDRDSRAL ETIDVDDYAV ACSSLATNSK LTAAFKRSAL RKAASLSQNG SSYRGIDETA
FAFSLIPASG EKKSLFLGSG KSHHFAVKSR DERINWMREL MLAKALKKGK EGGNEICVNG
NVI
//
