ID C4JGK5_UNCRE Unreviewed; 627 AA.
AC C4JGK5;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Phosphoenolpyruvate carboxykinase (ATP) {ECO:0000256|ARBA:ARBA00021932};
DE EC=4.1.1.49 {ECO:0000256|ARBA:ARBA00012363};
GN ORFNames=UREG_01196 {ECO:0000313|EMBL:EEP76347.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP76347.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC EC=4.1.1.49; Evidence={ECO:0000256|ARBA:ARBA00001389};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC family. {ECO:0000256|ARBA:ARBA00006052}.
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DR EMBL; CH476615; EEP76347.1; -; Genomic_DNA.
DR RefSeq; XP_002541680.1; XM_002541634.1.
DR AlphaFoldDB; C4JGK5; -.
DR STRING; 336963.C4JGK5; -.
DR GeneID; 8439880; -.
DR KEGG; ure:UREG_01196; -.
DR VEuPathDB; FungiDB:UREG_01196; -.
DR eggNOG; ENOG502QQI5; Eukaryota.
DR HOGENOM; CLU_018247_2_0_1; -.
DR InParanoid; C4JGK5; -.
DR OMA; TSHGCWL; -.
DR OrthoDB; 3740611at2759; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.228.20; -; 2.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR Gene3D; 2.170.8.10; Phosphoenolpyruvate Carboxykinase, domain 2; 1.
DR HAMAP; MF_00453; PEPCK_ATP; 1.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR InterPro; IPR015994; PEPCK_ATP_CS.
DR PANTHER; PTHR30031:SF0; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); 1.
DR PANTHER; PTHR30031; PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP; 1.
DR Pfam; PF01293; PEPCK_ATP; 2.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
DR PROSITE; PS00532; PEPCK_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432};
KW Kinase {ECO:0000313|EMBL:EEP76347.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000313|EMBL:EEP76347.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Transferase {ECO:0000313|EMBL:EEP76347.1}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 69013 MW; DC7F0E9F16DED5F5 CRC64;
MDPAPAASSP SASAPRASVH IPPNHPLPLD FLTSDFARQQ VAKQQHSNYH STSLRTMVST
SVNRTALHPT GVQPGKGHTE LEEELYETAH IDCERVAIIA NPSVAALYED ALVYETGTAI
TSSGALTAYS GAKTGRSPLD KRIVKESSSE NEIWWGPVNK PMTPEVWKIN RERAVDYLNT
RNRIYVIDGY AGWDERYRIN VRVVCARAYH ALFMRNMLIR PKREELEHFH PDYVIYNAGS
FPANRWTEGM TSATSVAINF AEKEMVILGT EYAGEMKKGV FTVLFYEMPI KHNVLTLHSS
ANQGQDGDVT LFFGLSGTGK TTLSADPKRA LIGDDEHCWS DRGVFNIEGG CYAKCIGLSA
EKEPDIFNAI RFGSVLENVV FNPETRVVDY DDATLTENTR CAYPIEYIDN AKIPCMAGAA
PVKHHPPHLR CSRCPPTHLE AHQRANHVPL HLGLHLPRWL ALRTIAEHKA NAWLLNTGWV
GAARVTTGGK RCPLKYTRAI LDAIHSGELA KVEYETYDTF NLHIPKSCPN VPSELLNPQR
SWTGSASFKD EVNKLGDLFN QNFKKYSEEA TPEVLAAAPI VVSASEATST AAVEPPVSAK
AAPASTVDPT QPVQVNGDHV HANGSSI
//
