ID C4JLR2_UNCRE Unreviewed; 943 AA.
AC C4JLR2;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEP78924.1};
GN ORFNames=UREG_03770 {ECO:0000313|EMBL:EEP78924.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP78924.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH476616; EEP78924.1; -; Genomic_DNA.
DR RefSeq; XP_002544253.1; XM_002544207.1.
DR AlphaFoldDB; C4JLR2; -.
DR STRING; 336963.C4JLR2; -.
DR GeneID; 8444146; -.
DR KEGG; ure:UREG_03770; -.
DR VEuPathDB; FungiDB:UREG_03770; -.
DR eggNOG; KOG1162; Eukaryota.
DR HOGENOM; CLU_006116_1_0_1; -.
DR InParanoid; C4JLR2; -.
DR OMA; GDMYCSL; -.
DR OrthoDB; 7162at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 2.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 486..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 696..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..426
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 563..779
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 45..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 897..924
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..943
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 108046 MW; B1F82568B8BBCB1B CRC64;
MKFAKELEQE LVPEWRAKYL NYKLGKKKIK AIARALRAIE QAPRTPGRRG FLSGHDGTPR
IGRPALPQFG PYRGSRSKDR FGRQSSYEET DILAGPANPY SQDTPFPERR PLKSPSRFAD
CAGGYGSIVT PQSNATRSTG LPSLELPDPA LDPNEANFPP CTRMVSANSL DSRANPTPGR
GRGRWNLQSS ILPGSRNVFR PRGGSVPPGR LTRRRSFLQR MFTSRVEHES PSANPPAEAF
LELRNRETEF FDFLDKELVK IESFYRLKEE EATERLRILK EQLHVMRDMR LEELRAKARL
KHQGGPSSDM RHDTDPAAKW TRPLSKSLNG LSKYDKISKE LAELPTPGST LHRTRNTENY
RDFVRRQEND VPYRSAKRKL KTALLEFYRG LELLKAYAYL NRKAFRKMNK KYDKATNVRP
TGRYMSEKVN NAWFVQSDLV ESHLVAVEDL YTRYFERGNR KVAVTKLRGK AARSLDYSPN
SFRNGLLFAA GLVFGIQGLV HAVGHLFNQN DDDDYDFDDL HVQTSYLLQI YGGYTLILLH
FIFFCLNCRV WTRSKINYVF VFEYDTRHVL DWRQLAEIPC FLVFLLGLVI WLNFRWVNEI
GGCCSQGCTL WSFEISSWEI CIALKHMPWA CSILYYMTLS LYRINKIESL RATFIVFALV
NAIYSSIWDV AMDWSLGNPF SRNPFLRDSL GFRKRWVYYM AMIIDPILRF NWIFYAIFTH
DVQHSAILSF LVSLSEVCRR GIWSIFRVEN EHCTNVSRFR ASRDVPLPYD LPSDTFDQHS
RPFESTTIQQ AAAGVPIAHL PPATPATGVD VERLAADNTT PSGMRHRHGT QPSETPGGTL
ARVGTMLANA HAEDFERRKR PGVVGSTHDH DKNQAHSHGH HDRDHGHGVH RRDSSTDDEE
EEEEDDDDDD DDEGVVESES EENGSNELDD PRIIEGVDGR FKN
//
