ID C4JMN2_UNCRE Unreviewed; 474 AA.
AC C4JMN2;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN ORFNames=UREG_04090 {ECO:0000313|EMBL:EEP79244.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP79244.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
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DR EMBL; CH476616; EEP79244.1; -; Genomic_DNA.
DR RefSeq; XP_002544573.1; XM_002544527.1.
DR AlphaFoldDB; C4JMN2; -.
DR STRING; 336963.C4JMN2; -.
DR GeneID; 8444793; -.
DR KEGG; ure:UREG_04090; -.
DR VEuPathDB; FungiDB:UREG_04090; -.
DR eggNOG; KOG2617; Eukaryota.
DR HOGENOM; CLU_022049_2_1_1; -.
DR InParanoid; C4JMN2; -.
DR OMA; VLEWLFK; -.
DR OrthoDB; 3513214at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR GO; GO:0006101; P:citrate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd06105; ScCit1-2_like; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR010109; Citrate_synthase_euk.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01793; cit_synth_euk; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF8; CITRATE SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU000441}.
FT ACT_SITE 310
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 356
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 411
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
SQ SEQUENCE 474 AA; 52082 MW; 73183317EDF34C25 CRC64;
MASTLRLGSA ALRSTSFASK PAVQSAAFNC FRSYSSAKSK SLKDTFADKL PGEVEKVKKL
RKEFGSKVLG EVTLDQVYGG ARGVKSLVWE GSVLDSEEGI RFRGYTIPEC QKLLPKAPGG
EEPLPEGLFW LLLTGEVPSE QQVRDLSAEW AARSDVPKFV EELLDRCPNT LHPMAQFSLA
VTALEHESSF AKAYAKGINK KDYWQYTFED SMDLIAKLPS IASKIYRNVF KDGKVAPIQK
DKDYGFNLAN QLGYGENKDF VELMRLYLTI HSDHEGGNVS AHTTHLVGSA LSSPMLSLAA
GLNGLAGPLH GLANQEVLVW LQKMKKAIGN DLSDQAIKDY LWSTLNAGQV VPGYGHAVLR
KTDPRYVSQR EFALRKLPDD PMFKLVSQVY KIAPGVLTEH GKTKNPYPNV DAHSGVLLQY
YGLTEASYYT VLFGVSRALG VLPQLIIDRA LGAPIERPKS FSTEAYAKLV GAKL
//
