ID   C4JQ03_UNCRE            Unreviewed;       480 AA.
AC   C4JQ03;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=FMN hydroxy acid dehydrogenase domain-containing protein {ECO:0000259|PROSITE:PS51349};
GN   ORFNames=UREG_03236 {ECO:0000313|EMBL:EEP78390.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP78390.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR   EMBL; CH476616; EEP78390.1; -; Genomic_DNA.
DR   RefSeq; XP_002543719.1; XM_002543673.1.
DR   AlphaFoldDB; C4JQ03; -.
DR   STRING; 336963.C4JQ03; -.
DR   GeneID; 8439667; -.
DR   KEGG; ure:UREG_03236; -.
DR   VEuPathDB; FungiDB:UREG_03236; -.
DR   eggNOG; KOG0538; Eukaryota.
DR   HOGENOM; CLU_020639_1_1_1; -.
DR   InParanoid; C4JQ03; -.
DR   OMA; WSYVAGG; -.
DR   OrthoDB; 1887365at2759; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02922; FCB2_FMN; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR   InterPro; IPR000262; FMN-dep_DH.
DR   InterPro; IPR037396; FMN_HAD.
DR   InterPro; IPR037458; L-MDH/L-LDH_FMN-bd.
DR   PANTHER; PTHR10578:SF82; CYTOCHROME B2, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07200)-RELATED; 1.
DR   PANTHER; PTHR10578; S -2-HYDROXY-ACID OXIDASE-RELATED; 1.
DR   Pfam; PF01070; FMN_dh; 1.
DR   SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR   SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR   PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058}.
FT   DOMAIN          89..458
FT                   /note="FMN hydroxy acid dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51349"
SQ   SEQUENCE   480 AA;  51996 MW;  3CFC9F2E2D7F1EAC CRC64;
     MGLTGTSREA QHRQQLLGGA LWKGVRCANI ILNLAGKDAT EEYDPIHPSG TLEENLQPEA
     CLGTVDPATL HKLTPKKAPE PPKTTEGRLP LSSLLNLDDV EKAATSQISR KAWGYYYSAA
     DDLISKSLNN TVYRSILLRP RVFIDCRKCD LTTTLLGHKL SSPVYVSPAA MARLAHPVGE
     AGIAAACSEF GTMQIISNNA SMTPEEIVKN ATPDQVFGWQ LYVQTEKRKS EAMLARIKKL
     KAIKFICLTL DAPVPTKRED DERTKYILNT DDTSDMLRNA GASSISTRGG GIGEQLFGGT
     DASLTWKTTL PWLAKHTDLP IILKGIQTHE DAYVASLHAP QVKGIILSNH GGRSMDTAPP
     AIHTLLEIRK FCPEVFDSLE VWVDGGIRRG TDVVKALCLG AKAVGIGRAA LFGLGAGGTD
     GVKRVLQILK QETKTAMRLL GVEKVEDLGM QHVNARAVER FIYDGPAGLD VLGTLLKAKM
//