ID C4JZR4_UNCRE Unreviewed; 1819 AA.
AC C4JZR4;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=UREG_07665 {ECO:0000313|EMBL:EEP82800.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP82800.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476619; EEP82800.1; -; Genomic_DNA.
DR RefSeq; XP_002582892.1; XM_002582846.1.
DR STRING; 336963.C4JZR4; -.
DR GeneID; 8438868; -.
DR KEGG; ure:UREG_07665; -.
DR VEuPathDB; FungiDB:UREG_07665; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_60_2_1; -.
DR InParanoid; C4JZR4; -.
DR OMA; YTIWEVT; -.
DR OrthoDB; 3305653at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SMART; SM01294; PKS_PP_betabranch; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002058}.
FT DOMAIN 775..852
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1346..1419
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1819 AA; 202935 MW; 04C7F4B3130121BA CRC64;
MDFPFEETGD SRKRKREIES TSNAGSKESR LKTQASDLES CIFPRVRASP APQKLHQTVY
RLEVECHDII SAEAVSRHLM TAWSILLAKY TGANKIRFGV LPESGTNQYE AAFEEWCASW
EPENSTADGV DLTNVCEWSF NNFKYRGRFN SCIAQQPKSC WFDAWTKLPD HPIELVLLVE
MTGRPHIELY SRSLLLDEGF LALLSAVLRH VLLDLTSDRP LQRLNMIPDE HRKQISDWNE
SVPKEPLAEC IHQLIRKQCD QHPDSQAVCA WDGNITYFEL ESLSSNVTKA LHRHDIGPET
VVPILFEKSK WTVVAILGTL KAGAAFVLLD PTHPLERLQG ICRDVRANVI LTSEVHQDTS
SKLATTVIMV PGLSIPAHTE DIIPLNGNRG KCMVNSSNVA YVSYTSGSTG KPKGIVIEHA
SVCTNAMASS EAQNLNGSSR VLQFASYAFD VSIHEILIPL ILGGCVCIPS EMQRVNNLQE
AIISLRVNWM ELTPSVARIL NPDEIPAVKT LVVGGESMPL VELTRWASRV RLIVAYGPAE
CTIVSTVQTR VGPDCDPSNI GRGYGGTTWV VDSEDHDSLV PIGTVGELVI GGPIVAREYL
GLPQQTKAAF VTNPPWATGS KFYKTGDLDT QVKLRGQRIE LGEIEHHAGD LFQGAAIAVE
MGKLHKGQSV LVLFVEWAHP KGDAGRENDD RGLLFRKPDQ LFSMRAHKAK TALTDMLPRY
MVPDLIVPLS AMPLSQTAKV DRKALRGIIS QLSKSDLNIY RFSSKHFGRQ DETNHHNGPL
EDEFVKAIAR TLSLDPRDIM DDDDFFHLGG DSISAIMLAA ETKKHLGLNL TVTDIFQYST
ISELRKQARK QHGPSSLVSL PGSVLPFSML GASDIETFKK IAVEQCGILP SQIEDIYPCS
PLQERFMART ARQPGAFQAR FAFRMSPTID WNRLRRAWNI AADAYPILRT RIINAAHLQL
SYSAFQVVVR GWNIEWLETY SNTRQIDGKW EKNMLFGTPL IYLIACRDSS RPGLTLVMHH
SLFDWWSYNK ILDAVQVAYE GQRLDPGHFS PFIKYIHEQN KSNAKEFWKR EFHGLKAVPS
FSHSFAGSSS HTVKWTHKDF PLRLCNQRGA TISAMIRLAW AMVVSQHTGL LDVDHNTALI
PFEQTGIQEI QQASPEAAMA CEFQSLLVQV QSMLQSMGHL LGLIADSPHE KTGSILGERR
RSMGKRSVFQ ENKLLASVES AARGYLGTNT QVAAEWIIPK SSRTSKLALF IGVNNSGVAS
QGSLILTRLG ENTRNRLSQL MLYLRAHLPR SSVPSCCIPV QLQYEPPKSC LLGELARLRE
AASKTTLVTL RSWENAKEGH YCRTPSPVES KLTSVLASVL RLESDDIDAD DDFVSLGCDS
LVAMQFAARC NRDGLMVTIS DIFEAKSVTR LALKLGNTPP TFPSVSNDFS LVRSVYKDLQ
RDAKGIEKVS KIARIVDAFP CTSPHLGLLP HDTSLQAHTI WEVSASGDVI DPFRLAEAWN
KLADRHAALR TVLLQSRFNP PRMFQIVLAS SPVEVEVVTD VEDQNIWPVV RKPFLSSSDR
DELPCKFTIY RTSTGRILCK LEGRHAFLDA TSVLIILQEL ASAYNGIVSS SEVSYLSWVS
YLRQWAKDSS HLHFWKSYLA GIKPCILTTH PQESKKNGIN SSQPHQKVLQ SHSATLMQTD
VLRRHCEKFR FSITNFFQVA WGLVLGKYTG LGDVCFGTLV SGRDAPVPHI NDIVGPLFNV
LVCRLSMPEH KSCHWLLKRN EAAIRDRLLH QYCSLKDVTR ASWDSDTPLF NTSLSVEQPL
SSEAGICFKE LETHEETEV
//
