ID C4KZW7_EXISA Unreviewed; 330 AA.
AC C4KZW7;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN OrderedLocusNames=EAT1b_1704 {ECO:0000313|EMBL:ACQ70630.1};
OS Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=360911 {ECO:0000313|EMBL:ACQ70630.1, ECO:0000313|Proteomes:UP000000716};
RN [1] {ECO:0000313|EMBL:ACQ70630.1, ECO:0000313|Proteomes:UP000000716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1283 / AT1b {ECO:0000313|Proteomes:UP000000716};
RX PubMed=21460088; DOI=10.1128/JB.00303-11;
RA Vishnivetskaya T.A., Lucas S., Copeland A., Lapidus A., Glavina Del Rio T.,
RA Dalin E., Tice H., Bruce D.C., Goodwin L.A., Pitluck S., Saunders E.,
RA Brettin T., Detter C., Han C., Larimer F., Land M.L., Hauser L.J.,
RA Kyrpides N.C., Ovchinnikova G., Kathariou S., Ramaley R.F., Rodrigues D.F.,
RA Hendrix C., Richardson P., Tiedje J.M.;
RT "Complete genome sequence of the Thermophilic Bacterium Exiguobacterium sp.
RT AT1b.";
RL J. Bacteriol. 193:2880-2881(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; CP001615; ACQ70630.1; -; Genomic_DNA.
DR RefSeq; WP_012727748.1; NC_012673.1.
DR AlphaFoldDB; C4KZW7; -.
DR STRING; 360911.EAT1b_1704; -.
DR KEGG; eat:EAT1b_1704; -.
DR eggNOG; COG0470; Bacteria.
DR HOGENOM; CLU_006229_4_5_9; -.
DR OrthoDB; 9810148at2; -.
DR Proteomes; UP000000716; Chromosome.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000313|EMBL:ACQ70630.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ACQ70630.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACQ70630.1}.
SQ SEQUENCE 330 AA; 37646 MW; 225C345C0DDF99E7 CRC64;
MRFQELSESQ TVVSRIIQNS IVSNKVGHAY IFSGDYEPYL LDTATLFAKA LFCESPDGAE
PCGVCRNCRR MDSKNIVDYI EVEPDGASIK KEQIQQLLSD LSLRGAEGDR QVYVIHQAHK
MTTQAANSLL KFFEEPGVGK LAILVTTQPQ LLLPTIRSRA QQLAFRPIDR AQLAQTMSEE
LSCTYDLAYL ALTVYPKWDD AKEALEQEWF VQAYGLVVQL IEVLTKRPQE LLLFAQEKWL
GHFKGRNELR VGLELFEHWL EEALHLKVRD TYAPKLFKNE AALYNAFIQN RSVTKLTHAI
ESVHAAIRRL EANVNPQLTF ERLSFDLQKG
//
