ID C4L6H8_EXISA Unreviewed; 694 AA.
AC C4L6H8;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Heparinase II/III family protein {ECO:0000313|EMBL:ACQ70009.1};
GN OrderedLocusNames=EAT1b_1081 {ECO:0000313|EMBL:ACQ70009.1};
OS Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=360911 {ECO:0000313|EMBL:ACQ70009.1, ECO:0000313|Proteomes:UP000000716};
RN [1] {ECO:0000313|EMBL:ACQ70009.1, ECO:0000313|Proteomes:UP000000716}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1283 / AT1b {ECO:0000313|Proteomes:UP000000716};
RX PubMed=21460088; DOI=10.1128/JB.00303-11;
RA Vishnivetskaya T.A., Lucas S., Copeland A., Lapidus A., Glavina Del Rio T.,
RA Dalin E., Tice H., Bruce D.C., Goodwin L.A., Pitluck S., Saunders E.,
RA Brettin T., Detter C., Han C., Larimer F., Land M.L., Hauser L.J.,
RA Kyrpides N.C., Ovchinnikova G., Kathariou S., Ramaley R.F., Rodrigues D.F.,
RA Hendrix C., Richardson P., Tiedje J.M.;
RT "Complete genome sequence of the Thermophilic Bacterium Exiguobacterium sp.
RT AT1b.";
RL J. Bacteriol. 193:2880-2881(2011).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
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DR EMBL; CP001615; ACQ70009.1; -; Genomic_DNA.
DR RefSeq; WP_012727128.1; NC_012673.1.
DR AlphaFoldDB; C4L6H8; -.
DR STRING; 360911.EAT1b_1081; -.
DR KEGG; eat:EAT1b_1081; -.
DR eggNOG; COG0627; Bacteria.
DR HOGENOM; CLU_399418_0_0_9; -.
DR OrthoDB; 7335480at2; -.
DR Proteomes; UP000000716; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.70; -; 1.
DR Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR InterPro; IPR008929; Chondroitin_lyas.
DR InterPro; IPR012480; Hepar_II_III.
DR InterPro; IPR031680; Hepar_II_III_N.
DR PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR Pfam; PF07940; Hepar_II_III; 1.
DR Pfam; PF16889; Hepar_II_III_N; 1.
DR SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..694
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002940282"
FT DOMAIN 110..393
FT /note="Heparin-sulfate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16889"
SQ SEQUENCE 694 AA; 78787 MW; D16DBD978A4FC627 CRC64;
MKRILLVLVL IGAWGSVTPT DSAQAATNPF HIRSVPNAIV YEMKSGKLTK VATYSTTKRY
AAISTSGWYY IALSGGKKVY IKKSQAKLLL ADPITRSNLT SSGTARLAHE YMRQMAPHVP
YEYERLSEAK AIDYANRALK GDWYVPSTPY RLSVPNIDTF DWHRDIPSSS SNSYPFQIHY
LTVLNQLTQA YNATNDTAYL KYGMRVVKSW TKAHPVANYK QYRWPYNDHG TSVRTFHLLN
FWDVYKSSSL YKDTAFTGLM LRTLHEHGTL LATSSFYKYE HNHGVFQDMA LTAIAQTFPQ
FDQSANWKTI ADSRLDKQIR HSITSDAVHL EHSPGYQAYM YHVLDRFVIW ADENRFTLPS
SMNRVEYMPK QLTYMVKPNG TLPIFGDTSG ARRTTSIIPH IDDFPQLAYA VSGGKEGSRP
PLTVKKISTQ YSFMREYWSA PPRAFNQATQ VMMTAGYHSS AHKHADDLSI DLYGLGRDFI
IETGRYGYTN RPERQRVFGV DAHNTIHRDG ANLDLSTSMR EKSKIVTVKN LGPSLLAMGE
SKLIGKGATH RRTLVYDKAQ TLVVYDRISS PTQEKFVQRF HLAEGLKLLQ SSMATQNVVY
GDSNGRTIQL MQLNLKNSSM RNSTSFVAVE DYEWKPRPQV ISYNTGKDVR YLTLIRLDQS
KTTIRSASVK VSGSNYIVTY TLSNKETRQI SVPI
//
