ID C4LAK5_TOLAT Unreviewed; 115 AA.
AC C4LAK5;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Iron-sulfur cluster insertion protein ErpA {ECO:0000256|HAMAP-Rule:MF_01380};
GN Name=erpA {ECO:0000256|HAMAP-Rule:MF_01380};
GN OrderedLocusNames=Tola_0580 {ECO:0000313|EMBL:ACQ92209.1};
OS Tolumonas auensis (strain DSM 9187 / TA4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Tolumonas.
OX NCBI_TaxID=595494 {ECO:0000313|EMBL:ACQ92209.1, ECO:0000313|Proteomes:UP000009073};
RN [1] {ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA Beller H.;
RT "Complete sequence of Tolumonas auensis DSM 9187.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACQ92209.1, ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RX PubMed=22180815; DOI=10.4056/sigs.2184986;
RA Chertkov O., Copeland A., Lucas S., Lapidus A., Berry K.W., Detter J.C.,
RA Del Rio T.G., Hammon N., Dalin E., Tice H., Pitluck S., Richardson P.,
RA Bruce D., Goodwin L., Han C., Tapia R., Saunders E., Schmutz J.,
RA Brettin T., Larimer F., Land M., Hauser L., Spring S., Rohde M.,
RA Kyrpides N.C., Ivanova N., Goker M., Beller H.R., Klenk H.P., Woyke T.;
RT "Complete genome sequence of Tolumonas auensis type strain (TA 4).";
RL Stand. Genomic Sci. 5:112-120(2011).
CC -!- FUNCTION: Required for insertion of 4Fe-4S clusters for at least IspG.
CC {ECO:0000256|HAMAP-Rule:MF_01380}.
CC -!- COFACTOR:
CC Name=iron-sulfur cluster; Xref=ChEBI:CHEBI:30408;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01380};
CC Note=Binds 1 iron-sulfur cluster per subunit. {ECO:0000256|HAMAP-
CC Rule:MF_01380};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01380}.
CC -!- SIMILARITY: Belongs to the HesB/IscA family. {ECO:0000256|HAMAP-
CC Rule:MF_01380}.
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DR EMBL; CP001616; ACQ92209.1; -; Genomic_DNA.
DR RefSeq; WP_012728808.1; NC_012691.1.
DR AlphaFoldDB; C4LAK5; -.
DR STRING; 595494.Tola_0580; -.
DR KEGG; tau:Tola_0580; -.
DR eggNOG; COG0316; Bacteria.
DR HOGENOM; CLU_069054_5_3_6; -.
DR OrthoDB; 9801228at2; -.
DR Proteomes; UP000009073; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProt.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.300.12; HesB-like domain; 1.
DR HAMAP; MF_01380; Fe_S_insert_ErpA; 1.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR017870; FeS_cluster_insertion_CS.
DR InterPro; IPR023063; FeS_cluster_insertion_RrpA.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR NCBIfam; TIGR00049; iron-sulfur cluster assembly accessory protein; 1.
DR PANTHER; PTHR43011; IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43011:SF1; IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL; 1.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR SUPFAM; SSF89360; HesB-like domain; 1.
DR PROSITE; PS01152; HESB; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|HAMAP-Rule:MF_01380};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|HAMAP-
KW Rule:MF_01380};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|HAMAP-
KW Rule:MF_01380}; Reference proteome {ECO:0000313|Proteomes:UP000009073}.
FT DOMAIN 10..110
FT /note="FeS cluster biogenesis"
FT /evidence="ECO:0000259|Pfam:PF01521"
FT BINDING 43
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01380"
FT BINDING 107
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01380"
FT BINDING 109
FT /ligand="iron-sulfur cluster"
FT /ligand_id="ChEBI:CHEBI:30408"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01380"
SQ SEQUENCE 115 AA; 12249 MW; 036BFD48572B808B CRC64;
MSDVAVQFPI EMTDAAAAKV KTLITEEENP ELKLRVYITG GGCSGFQYGF TFDEKINEGD
TVVEKDGVIM VVDGMSLQYL VGGVVDYIDG LEGSRFTVTN PNATTTCGCG SSFSV
//
