ID C4LCA0_TOLAT Unreviewed; 849 AA.
AC C4LCA0;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Diguanylate cyclase with PAS/PAC sensor {ECO:0000313|EMBL:ACQ94404.1};
GN OrderedLocusNames=Tola_2811 {ECO:0000313|EMBL:ACQ94404.1};
OS Tolumonas auensis (strain DSM 9187 / TA4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Tolumonas.
OX NCBI_TaxID=595494 {ECO:0000313|EMBL:ACQ94404.1, ECO:0000313|Proteomes:UP000009073};
RN [1] {ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA Beller H.;
RT "Complete sequence of Tolumonas auensis DSM 9187.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACQ94404.1, ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RX PubMed=22180815; DOI=10.4056/sigs.2184986;
RA Chertkov O., Copeland A., Lucas S., Lapidus A., Berry K.W., Detter J.C.,
RA Del Rio T.G., Hammon N., Dalin E., Tice H., Pitluck S., Richardson P.,
RA Bruce D., Goodwin L., Han C., Tapia R., Saunders E., Schmutz J.,
RA Brettin T., Larimer F., Land M., Hauser L., Spring S., Rohde M.,
RA Kyrpides N.C., Ivanova N., Goker M., Beller H.R., Klenk H.P., Woyke T.;
RT "Complete genome sequence of Tolumonas auensis type strain (TA 4).";
RL Stand. Genomic Sci. 5:112-120(2011).
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DR EMBL; CP001616; ACQ94404.1; -; Genomic_DNA.
DR RefSeq; WP_015879853.1; NC_012691.1.
DR AlphaFoldDB; C4LCA0; -.
DR STRING; 595494.Tola_2811; -.
DR KEGG; tau:Tola_2811; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG3447; Bacteria.
DR eggNOG; COG3852; Bacteria.
DR HOGENOM; CLU_000445_126_1_6; -.
DR OrthoDB; 9804645at2; -.
DR Proteomes; UP000009073; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 298..368
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 372..424
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 500..552
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 630..682
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 714..847
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 849 AA; 95843 MW; 5C9777438439BDAF CRC64;
MRKEFAASVS LRPWWLRILT ITGLGLVACL NATVAPQQPG IITSLWYVNA LTIVTLLYHQ
PCFRALLLAG YTVGLSAGYW LNHVSGTAHL TLMLANLAEV LLAVYLLERS QSARCFYFNI
DAALKLGIFG ILLPPLAGAL LAASGFALST PWHWSETGIT WYINSVICSI SAMPLLLLIK
HRRWNRDQPW LLALNLLLLL GYTALVLKYF PFPFVYLGLG LALIAIRNGV FGAALAGFLV
SFCIAVFIRM AWFAWPQYDQ HLLMLFVYLP ILITLIPPLL LAIFVDTLHT REQQLLARES
MFREAMEASA VGMALVSTDG QLLKVNPALC HMLDYSETEL ADLSWSQLIH PDDLGMEQRY
QQRLLNNQQS SYRLEVRYRR KNGQMIWVLL VVSMVRDDRG LPHYFVLQAE DIDRRRRSEE
RERELFNRYL LAAEAGQVGV WEWRPSEQQM NWDERMFDLY ALDRHHIVPS FSVWKSCIYP
DDLPRILKEI SAALNETNVL DSEFRVKHYD DSIHYLRIHA MVERDAVGGV WRMVGTNWDI
TELRVLMNDL SRERELLRTT LLSIGEAVVM TDQNVRIIFM NPAAEHMLDC SNRKASHRSV
DRIMHLVDAD GHALENPLHT ALRQRRLIHL SNDAYLKKAD GSMTAIQDSA APILRNNDEL
LGGVLVFSDV TEMRALQKQL GYQASHDPLT GLINRSAFET ILQDVVKESV MTAGQSVLVY
LDLDYFKRVN DTAGHAAGDE LLRQLAGVMS SRMRASDIVA RLGGDEFGLI LRNCSVEYAE
SFMNGLISEI CKFEFCWNEQ IFHVGASAGL APVNGQFSAF SALLASADQA CYAAKRAGRG
QVKIVGTSF
//
