ID C4R015_KOMPG Unreviewed; 441 AA.
AC C4R015;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene e {ECO:0000313|EMBL:CAY68839.1};
GN OrderedLocusNames=PAS_chr2-1_0229 {ECO:0000313|EMBL:CAY68839.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY68839.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY68839.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
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DR EMBL; FN392320; CAY68839.1; -; Genomic_DNA.
DR RefSeq; XP_002491119.1; XM_002491074.1.
DR AlphaFoldDB; C4R015; -.
DR SMR; C4R015; -.
DR EnsemblFungi; CAY68839; CAY68839; PAS_chr2-1_0229.
DR GeneID; 8198778; -.
DR KEGG; ppa:PAS_chr2-1_0229; -.
DR eggNOG; KOG1729; Eukaryota.
DR HOGENOM; CLU_754582_0_0_1; -.
DR InParanoid; C4R015; -.
DR OrthoDB; 38671at2759; -.
DR Proteomes; UP000000314; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23164; EARLY ENDOSOME ANTIGEN 1; 1.
DR PANTHER; PTHR23164:SF30; LD23155P; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 329..394
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 64..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 441 AA; 49237 MW; D34473EA729237A8 CRC64;
MSSNLKIDSS IRVIDEQSAD FDQDSPVLSF KKQPIKTRTA SCSTISNLTP DFNSYHLTLK
GSFRDSSEVS STQDKTQPAQ TDNNPDDLDY DAKIRAPKMS SQSLFKSNPI KIAQHEPFQC
CDISQNSKDQ ATKPGSVETS QTDNKEFSRN TSNLSNDSLT SAETKVAEEV TDKTNSTFTP
ATFDINQPLR RHSIDEISSD LSNTLPGFST NASYSRLDNL QNAQNGNNPM SFSNRGSRNG
ISGPIRQINE PKTPNYVPAV LRPSSSHSLV VGNTPQFQLG SSSPLPDEED DNSSYDDDKL
YHYSSSENHA NAARFPYTMV PIKSHWLQNN KRSSCMDCQV KFSLLFRRHH CRHCGDIFCS
NCLTQRASLN LMAKFDLVHG MKSKVCNGCA KSWNQYLVKQ YNNNVGSSVS KLQVKQTVPD
EDPQRERMGS IVPSDWTWSS F
//
