ID   C4R163_KOMPG            Unreviewed;       360 AA.
AC   C4R163;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1) {ECO:0000313|EMBL:CAY69237.1};
GN   OrderedLocusNames=PAS_chr2-1_0601 {ECO:0000313|EMBL:CAY69237.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY69237.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY69237.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN392320; CAY69237.1; -; Genomic_DNA.
DR   RefSeq; XP_002491517.1; XM_002491472.1.
DR   AlphaFoldDB; C4R163; -.
DR   STRING; 644223.C4R163; -.
DR   EnsemblFungi; CAY69237; CAY69237; PAS_chr2-1_0601.
DR   GeneID; 8198037; -.
DR   KEGG; ppa:PAS_chr2-1_0601; -.
DR   eggNOG; KOG0531; Eukaryota.
DR   HOGENOM; CLU_044236_0_0_1; -.
DR   InParanoid; C4R163; -.
DR   OMA; EVWASYN; -.
DR   OrthoDB; 8274at2759; -.
DR   Proteomes; UP000000314; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR   GO; GO:0000164; C:protein phosphatase type 1 complex; IEA:EnsemblFungi.
DR   GO; GO:0072542; F:protein phosphatase activator activity; IEA:EnsemblFungi.
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; IEA:EnsemblFungi.
DR   GO; GO:0007059; P:chromosome segregation; IEA:EnsemblFungi.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IEA:EnsemblFungi.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973:SF23; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7; 1.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF12799; LRR_4; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00365; LRR_SD22; 10.
DR   SMART; SM00369; LRR_TYP; 5.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 8.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   360 AA;  41056 MW;  93205B6C2548C19D CRC64;
     MSKEEEKAAL NSSDNNSIYE TDPEDVQAPG NPISTLDTAT GFSLIDDTNP QEIAADEDLA
     DELASDLEYL DLVHLKVKSL ENLNLDRFAQ LTGICLRQNL VDSLVPLKAI SKKDQVTELD
     FYDNRINHIS KHVNEFENLE VLDLSFNKIK NIKNVDRLSK LKKLYLVQNK VHEIKNISNL
     KSLETLELGG NKLTEIGEEL LNLSSITDLW LGKNYIQRLQ NLDSLKNLEI LSIQSNRLTK
     IEGLEELVNL RELYLADNGI SKIENLDKNT KLEVLDLTSN KIEHLENMSH LTSLTDLWFS
     YNKISSFAEV EKELSKLPQL DTVYFEHNPI QTENPTSYRR KLKLILGSSL QKIDATYIRS
//