ID C4R5G4_KOMPG Unreviewed; 791 AA.
AC C4R5G4;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 86.
DE SubName: Full=Dynamin-related GTPase {ECO:0000313|EMBL:CAY70800.1};
GN OrderedLocusNames=PAS_chr3_0751 {ECO:0000313|EMBL:CAY70800.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY70800.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY70800.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR EMBL; FN392321; CAY70800.1; -; Genomic_DNA.
DR RefSeq; XP_002492979.1; XM_002492934.1.
DR AlphaFoldDB; C4R5G4; -.
DR SMR; C4R5G4; -.
DR STRING; 644223.C4R5G4; -.
DR EnsemblFungi; CAY70800; CAY70800; PAS_chr3_0751.
DR GeneID; 8200444; -.
DR KEGG; ppa:PAS_chr3_0751; -.
DR eggNOG; KOG0446; Eukaryota.
DR HOGENOM; CLU_008964_5_0_1; -.
DR InParanoid; C4R5G4; -.
DR OMA; KICHNCG; -.
DR OrthoDB; 1052588at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0032153; C:cell division site; IEA:EnsemblFungi.
DR GO; GO:0005739; C:mitochondrion; IEA:EnsemblFungi.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0034643; P:establishment of mitochondrion localization, microtubule-mediated; IEA:EnsemblFungi.
DR GO; GO:0090149; P:mitochondrial membrane fission; IEA:EnsemblFungi.
DR GO; GO:0000001; P:mitochondrion inheritance; IEA:EnsemblFungi.
DR GO; GO:0007031; P:peroxisome organization; IEA:EnsemblFungi.
DR GO; GO:0140572; P:vacuole fission; IEA:EnsemblFungi.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF21; DYNAMIN-1-LIKE PROTEIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT DOMAIN 25..339
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 704..791
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
FT REGION 79..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..575
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 88512 MW; 65241FB5D11D48FA CRC64;
MSALKDLIPV VNKLQDIVTT TNLTELDLPL LTIIGSQSAG KSSVLENIVG KDFLPRGTGI
VTRRPLILQL INIQPDDPLV YQNSSSSGPG YPESSDVAEE PTLEDHLRKN ADPSGADDQS
PVAEWGQFLH LPGKRFYNFQ EIRREIEAET ARIAGKNKGI SRVPINLKIY SPNVLNLTMV
DLPGLTKIPI GDQPTDIERQ IKNLILEYIA RPNAIILAVS PANVDLVNSE ALKLARQVDP
QGKRTIGVLS KVDLMDHGTN ALDILTGKVY PLKLGFIGVV NRSQQDISVN KALFDSLRAE
EEFFQSHAAY RNIANRCGTK YLARVLNQTL MNHIRERLPD IKAKLNTLMG QTEQELASYG
DMGSVSESNK GGLILQLMTK FATNFVNSIE GNSSSVSTKE LCGGARIYSI YNDVFGSSLL
SINPTASLSV SDIRTAIRNS TGPRPSLFVP ELAFDLLVKP QIKLLEGPSH RCVELVYEEL
MKICHNCGSP ELGRYPKLQA KLIEVISDLL RERLGPTTQY VESLIDIHRA YINTNHPNFV
GAAAAMTSVV EERKKQKEES MRIKTREEKK KSTETGSASS PDSPKELLLE NGSTNSSVSQ
LIEKHRKSSD SVHGDDSRHA QQQNGDNKES FLNFFFGKDS QQENQQQQLH QNKPATRPFQ
FAEDSETLHF SNEPEAQTAI QRMDALNLHK DTEAHLSERE QLECELIRRL IDSYFDIVRE
MIQDQVPKAV MCLLVNYTKE CVQNRLVSKL YKESMFDELL FEDENLAQER EKCQKLLNTY
KEASEIINEV I
//
