ID C4R5I3_KOMPG Unreviewed; 192 AA.
AC C4R5I3;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 71.
DE RecName: Full=Anaphase-promoting complex subunit 10 {ECO:0000256|PIRNR:PIRNR028841};
GN OrderedLocusNames=PAS_chr3_1218 {ECO:0000313|EMBL:CAY70819.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY70819.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY70819.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 {ECO:0000313|EMBL:CAY70819.1};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- FUNCTION: Component of the anaphase promoting complex/cyclosome
CC (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex
CC that controls progression through mitosis and the G1 phase of the cell
CC cycle. {ECO:0000256|PIRNR:PIRNR028841}.
CC -!- SIMILARITY: Belongs to the APC10 family.
CC {ECO:0000256|ARBA:ARBA00006762, ECO:0000256|PIRNR:PIRNR028841}.
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DR EMBL; FN392321; CAY70819.1; -; Genomic_DNA.
DR RefSeq; XP_002492998.1; XM_002492953.1.
DR AlphaFoldDB; C4R5I3; -.
DR SMR; C4R5I3; -.
DR STRING; 644223.C4R5I3; -.
DR EnsemblFungi; CAY70819; CAY70819; PAS_chr3_1218.
DR GeneID; 8200461; -.
DR KEGG; ppa:PAS_chr3_1218; -.
DR eggNOG; KOG3437; Eukaryota.
DR HOGENOM; CLU_039415_2_1_1; -.
DR InParanoid; C4R5I3; -.
DR OMA; FITIEFP; -.
DR OrthoDB; 20429at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:EnsemblFungi.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:EnsemblFungi.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd08366; APC10; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR016901; APC10/Doc1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12936; ANAPHASE-PROMOTING COMPLEX 10; 1.
DR PANTHER; PTHR12936:SF0; ANAPHASE-PROMOTING COMPLEX SUBUNIT 10; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR PIRSF; PIRSF028841; APC10_sub; 1.
DR SMART; SM01337; APC10; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51284; DOC; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR028841};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR028841};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR028841};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR028841}.
FT DOMAIN 1..185
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
SQ SEQUENCE 192 AA; 21927 MW; 1058A6E4ED28CAC3 CRC64;
MEQIDNHNLY QKGKLFTKKG LVEISSLAWW SVSSYKHNNG LKELREDNPD TYWQSDGNLP
HSLKLHFSKK VSVERISLFT NYQLDESYSP QVISVYSGNG EHDLIKVTTC ELVEPIGWSH
IIFNGVREDG ILNTFFIKLS FESNHQSGKD THIRSLKVCS PRNIVNKSDS TDLINCEVKP
TSIRLISESG IR
//
