ID C4R625_KOMPG Unreviewed; 270 AA.
AC C4R625;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 08-NOV-2023, entry version 61.
DE RecName: Full=Phosphoglycerate mutase-like protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=PAS_chr3_0950 {ECO:0000313|EMBL:CAY71011.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71011.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY71011.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
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DR EMBL; FN392321; CAY71011.1; -; Genomic_DNA.
DR RefSeq; XP_002493190.1; XM_002493145.1.
DR AlphaFoldDB; C4R625; -.
DR SMR; C4R625; -.
DR STRING; 644223.C4R625; -.
DR EnsemblFungi; CAY71011; CAY71011; PAS_chr3_0950.
DR GeneID; 8200301; -.
DR KEGG; ppa:PAS_chr3_0950; -.
DR eggNOG; ENOG502QQ8J; Eukaryota.
DR HOGENOM; CLU_033323_3_1_1; -.
DR InParanoid; C4R625; -.
DR OMA; MRLFCMR; -.
DR OrthoDB; 118474at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:EnsemblFungi.
DR GO; GO:0032366; P:intracellular sterol transport; IEA:EnsemblFungi.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR PANTHER; PTHR46192; BROAD-RANGE ACID PHOSPHATASE DET1; 1.
DR PANTHER; PTHR46192:SF11; BROAD-RANGE ACID PHOSPHATASE DET1; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT ACT_SITE 12
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 98
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 11..18
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 68
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 270 AA; 31539 MW; F5952C2FE6E5FB46 CRC64;
MARPRLILLI RHGESEGNCD KSVNRHTPNH KVPLTQKGRE QAFNAGIELS RLLEKQDRVL
FYTSPYLRAR QTLDGILEGL GDYNDHNYAV YEEPRMREQD FGNFQGGPEK MQRIWKERAH
YGHFFYRIPN GESAADVYDR CAGFNETLFR QFQNHKFADV LVLVTHGIWA RVFLMKWFRW
SVEEFEGLRN IPHCQFIQMV KGENQRYTLT TPLLRWREGD EDRVEEIRKA VQFRSGDLGK
EALAYIVAAE REAAAGRSEG PITYDDGDDH
//
