ID   C4R6E7_KOMPG            Unreviewed;       783 AA.
AC   C4R6E7;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN   OrderedLocusNames=PAS_chr3_1070 {ECO:0000313|EMBL:CAY71133.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71133.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY71133.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC       {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC       {ECO:0000256|RuleBase:RU365072}.
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DR   EMBL; FN392321; CAY71133.1; -; Genomic_DNA.
DR   RefSeq; XP_002493312.1; XM_002493267.1.
DR   AlphaFoldDB; C4R6E7; -.
DR   SMR; C4R6E7; -.
DR   STRING; 644223.C4R6E7; -.
DR   EnsemblFungi; CAY71133; CAY71133; PAS_chr3_1070.
DR   GeneID; 8200030; -.
DR   KEGG; ppa:PAS_chr3_1070; -.
DR   eggNOG; KOG1964; Eukaryota.
DR   HOGENOM; CLU_023045_0_0_1; -.
DR   InParanoid; C4R6E7; -.
DR   OMA; YKVYTKH; -.
DR   OrthoDB; 2718743at2759; -.
DR   Proteomes; UP000000314; Chromosome 3.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:UniProtKB-UniRule.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3450.20; -; 1.
DR   Gene3D; 1.20.190.50; -; 1.
DR   InterPro; IPR007252; Nup84/Nup107.
DR   PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR   PANTHER; PTHR13003; NUP107-RELATED; 1.
DR   Pfam; PF04121; Nup84_Nup100; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|RuleBase:RU365072};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW   Translocation {ECO:0000256|ARBA:ARBA00023010,
KW   ECO:0000256|RuleBase:RU365072};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
SQ   SEQUENCE   783 AA;  91161 MW;  C7CC38F816A55082 CRC64;
     MKPEKFEGDQ DTIRADVWIE FSKILKRYRL KLDSVDLFEI VSEFKRVCSE TIIEADREGF
     SPDILENWIL ETKFWNLVEM LIKYRFFVDF EKTNSDTDVN PYRTDLSVKE QIISANSNLK
     ELMVIISWLT QNFNLDLVDR DPFLPDSKDS ELQANKWFHT RIDIQSNEDK PTLVRQLDAD
     APLRGKDNNR LNEKDVQYDS NFFERVFRLL LEGNIDEISQ LCKETNNWSF ALVLRGLKDF
     IDPELNGSFS RDDDEDIGVN SQETKRCIGI KNRKLWRKTV YQLSLNEQLT DKERGVYGYM
     CGSHEVPVKL TNSWDRQLLI YCNNILQHDM EIELERVTRP LTGSADLQLP LPPKKHRDLN
     DTLNALASSN NPSIREQSQH SIRVLSGSLI TNSIGELLKN SSDLLNEMIT GGDESKTEAD
     LIKESYLLRI LVHLAIFMRM LDDSIISGSN LNNLIKVYIA RLSLYKQYDS IPVYISFIST
     HADTIETYTF ILSSMITDKA DRLKQLKEMR ELELPLETIV KRTVQRVFEA TEYLYSNHTE
     IIISADVSHI DYKLMHTFDW FVDADMSYEA LDAIIVLMRR FLLNGKVAAL VELHEHIAIQ
     KILDDYKLRD EVWKNHGSDL ALNLTTIPEY KLMEVSQYLK LVQISKQLHE YEYQGTLEEP
     SRSVNLINSL TNNLKQIILS FLEGLYNPPA ESEVSPEDKL MYQELRELYI PIWIDTLFDI
     LVENRKISTV YVKEAADVVN LIADETNKFY YMLLKVGKLE PFLQKFALIT TDIFDDYEDG
     IFV
//