ID C4R6J0_KOMPG Unreviewed; 271 AA.
AC C4R6J0;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE SubName: Full=Protein that localizes to the nucleus and is involved in transcription regulation {ECO:0000313|EMBL:CAY71176.1};
GN OrderedLocusNames=PAS_chr3_1109 {ECO:0000313|EMBL:CAY71176.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71176.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY71176.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
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DR EMBL; FN392321; CAY71176.1; -; Genomic_DNA.
DR RefSeq; XP_002493355.1; XM_002493310.1.
DR AlphaFoldDB; C4R6J0; -.
DR SMR; C4R6J0; -.
DR EnsemblFungi; CAY71176; CAY71176; PAS_chr3_1109.
DR GeneID; 8200066; -.
DR KEGG; ppa:PAS_chr3_1109; -.
DR eggNOG; KOG0703; Eukaryota.
DR HOGENOM; CLU_1027161_0_0_1; -.
DR InParanoid; C4R6J0; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08204; ArfGap; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF9; PROTEIN GTS1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 9..127
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 135..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 271 AA; 30962 MW; 567591BF591F72BD CRC64;
MAKASRSESL LLEIINSSEN SNKCGECGSC YPTWASWNLG VLLCGRCASL HRVLGFDVSR
VKSLSLEEWN EKELQQLKVL GNKKNTKKWN PKRIPFPFDE DDKTGMEAWI KDKYIKGKFL
NESYEELDYN LGYPRSSTKS ASKSPSFESD DFSRIGNRSY TKLSSSKTES RHNSEVPPPL
PRRRENSLTA NKITTINSET DWLSRPSSSP APAHHQQSTF QPMIISEAPD QTFMQPQIYQ
YVDPIDGLLK YVDQNGQQYI DSAQYQNFYQ S
//
