ID   C4R710_KOMPG            Unreviewed;       913 AA.
AC   C4R710;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
GN   OrderedLocusNames=PAS_chr4_0160 {ECO:0000313|EMBL:CAY71385.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71385.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY71385.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC       ECO:0000256|RuleBase:RU000394}.
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DR   EMBL; FN392322; CAY71385.1; -; Genomic_DNA.
DR   RefSeq; XP_002493564.1; XM_002493519.1.
DR   AlphaFoldDB; C4R710; -.
DR   STRING; 644223.C4R710; -.
DR   EnsemblFungi; CAY71385; CAY71385; PAS_chr4_0160.
DR   GeneID; 8201070; -.
DR   KEGG; ppa:PAS_chr4_0160; -.
DR   eggNOG; KOG0243; Eukaryota.
DR   HOGENOM; CLU_001485_33_3_1; -.
DR   InParanoid; C4R710; -.
DR   OrthoDB; 536293at2759; -.
DR   Proteomes; UP000000314; Chromosome 4.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007051; P:spindle organization; IEA:UniProt.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR047149; KIF11-like.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47970; KINESIN-LIKE PROTEIN KIF11; 1.
DR   PANTHER; PTHR47970:SF12; KINESIN-LIKE PROTEIN KIF11; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|RuleBase:RU000394}; Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Microtubule {ECO:0000256|RuleBase:RU000394};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|RuleBase:RU000394};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|RuleBase:RU000394};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT   DOMAIN          7..355
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          839..913
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          157..184
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          401..449
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        839..879
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         104..111
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   913 AA;  102966 MW;  41CC13DE0780AC31 CRC64;
     MESQDESITV VVRCRGRSSK EVQLKQPIIV DVPSEFDSDS VTRTVSVNTS HDSSLSSQIT
     STKSYTVDQS FGPAVDQEMV FQSVAEPLFE EFIRGYNCTI FAYGQTGTGK THTMCGDGRE
     IEGSLSPDAG IIPRLLFKLF DALNQKNIDF VVKCSFVELY NEELKDLLGN INSSKSRLRI
     YEQRDGSKPL IKIDGLEERH IQDAHQGMKL LQKGIRQRKT ASTKLNEMSS RSHTIFTVTL
     WQKLPNDVDD KYSVAKMNLV DLAGSENIHR SGAVNARARE AGVINQSLLT LGRVINSLVD
     KASYIPYRES KLTRLLQDSL GGKTKTVLIA NISPTRADHH ETISTLEYAA KAKNICNAVQ
     VGGFVSKNLL LKDLASEITR LKLDLIATRS KEGVFLDDSN YNQLISEQEN LKTEVRELQI
     SNRALRLKLE NTSNTLKKEK EYHSKIEQEL TAYKNSNITI QNSLKERNNQ LIDISLITNN
     IAQTAEKDLK QVKSFQELVA RQLKHRTLQE LQASLNHLMR KNNAKDITID EDTGMLRVLL
     KDFESMLQNT LLGMTKDVIE PSVNTKATVS ELRSHLQDLG QLLRSQVDDN LSMISSLEQQ
     TRSISRYIEK GMFKNKDQIV ENCLSQLKAD IERETLKFQE VMFSKVRDSV SSATKTLASS
     ETNEITKIYQ SWIGSTSDAV MNRKSREDEF RKSFEISEAT TEQKLSEIDE RTTNGAESLR
     EHQENLLQKS YLLSSNGPVC RAVDQIDIKF NTVGNCRTHL HDKLHSVYEQ LSHYTHQVNQ
     VVNQNRDDES SRLEVERFLR SFKAVLKSSG LEEDFKMRQR ETEATVGEIQ QLSVRELNLD
     QDPDSSGSAN PTTRVQVLTP RKNSLHTPGV GSSTPQGLKR PRSNEDKENT LLASPKHPRI
     FGDGASLLGN QEK
//