ID C4R7F5_KOMPG Unreviewed; 377 AA.
AC C4R7F5;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Component of the septin ring of the mother-bud neck that is required for cytokinesis {ECO:0000313|EMBL:CAY71530.1};
GN OrderedLocusNames=PAS_chr4_0293 {ECO:0000313|EMBL:CAY71530.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY71530.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY71530.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SUBCELLULAR LOCATION: Bud neck {ECO:0000256|ARBA:ARBA00004266}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR EMBL; FN392322; CAY71530.1; -; Genomic_DNA.
DR RefSeq; XP_002493709.1; XM_002493664.1.
DR AlphaFoldDB; C4R7F5; -.
DR SMR; C4R7F5; -.
DR STRING; 644223.C4R7F5; -.
DR EnsemblFungi; CAY71530; CAY71530; PAS_chr4_0293.
DR GeneID; 8200735; -.
DR KEGG; ppa:PAS_chr4_0293; -.
DR eggNOG; KOG2655; Eukaryota.
DR HOGENOM; CLU_017718_8_0_1; -.
DR InParanoid; C4R7F5; -.
DR OMA; RNRTIMA; -.
DR OrthoDB; 2732954at2759; -.
DR Proteomes; UP000000314; Chromosome 4.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR GO; GO:0032156; C:septin cytoskeleton; IEA:UniProt.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF109; SEPTIN-1; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT DOMAIN 21..295
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT COILED 313..372
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 377 AA; 43472 MW; 36E66D19D65A1021 CRC64;
MSEQIGISNL PNQRYKLASK NGGYFTLMVA GESGLGKTTF INTLFQTTLK QSPDAKVRHK
SDIHKTVEIE ITRAELEEKN YTLRLNVIDT PGFGDNINNR NAFQPIVDFI DDQHDLYMKQ
EQQPERARAH DLRVHACLYF IRPTGHTLKP LDVEVMKKLG SRCNLIPVIA KADTLSPNEM
LDFKNNIRAI IEAQDIRIYS PPIDHEDQGA AEHARQLIES MPFAVIGSED LHEVTPGAAP
VAGRKYPWGI VEVENDQHCD FRKLRSLLLR INMLDLILST EELHYETYRS LRLSDDVPER
SHEISRINNP KFLEEEKALR QAFSNQVKVE EQRFKQWEQN INTERARLNH DLSEIQEQIK
QMEDQIKKLE ISKGIKV
//
