ID C4R920_KOMPG Unreviewed; 335 AA.
AC C4R920;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 73.
DE RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1 {ECO:0000256|ARBA:ARBA00022083};
GN OrderedLocusNames=PAS_chr4_0826 {ECO:0000313|EMBL:CAY72095.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY72095.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY72095.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SIMILARITY: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00025804}.
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DR EMBL; FN392322; CAY72095.1; -; Genomic_DNA.
DR RefSeq; XP_002494274.1; XM_002494229.1.
DR AlphaFoldDB; C4R920; -.
DR SMR; C4R920; -.
DR STRING; 644223.C4R920; -.
DR EnsemblFungi; CAY72095; CAY72095; PAS_chr4_0826.
DR GeneID; 8201226; -.
DR KEGG; ppa:PAS_chr4_0826; -.
DR eggNOG; KOG1521; Eukaryota.
DR HOGENOM; CLU_038421_0_1_1; -.
DR InParanoid; C4R920; -.
DR OMA; ECLRHPE; -.
DR OrthoDB; 5472982at2759; -.
DR Proteomes; UP000000314; Chromosome 4.
DR GO; GO:0005736; C:RNA polymerase I complex; IEA:EnsemblFungi.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:EnsemblFungi.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0001054; F:RNA polymerase I activity; IEA:EnsemblFungi.
DR GO; GO:0001056; F:RNA polymerase III activity; IEA:EnsemblFungi.
DR GO; GO:0006363; P:termination of RNA polymerase I transcription; IEA:EnsemblFungi.
DR GO; GO:0006386; P:termination of RNA polymerase III transcription; IEA:EnsemblFungi.
DR GO; GO:0006362; P:transcription elongation by RNA polymerase I; IEA:EnsemblFungi.
DR GO; GO:0006361; P:transcription initiation at RNA polymerase I promoter; IEA:EnsemblFungi.
DR GO; GO:0006384; P:transcription initiation at RNA polymerase III promoter; IEA:EnsemblFungi.
DR GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IEA:EnsemblFungi.
DR CDD; cd07032; RNAP_I_II_AC40; 1.
DR Gene3D; 2.170.120.12; DNA-directed RNA polymerase, insert domain; 1.
DR Gene3D; 3.30.1360.10; RNA polymerase, RBP11-like subunit; 1.
DR HAMAP; MF_00320; RNApol_arch_Rpo3; 1.
DR InterPro; IPR001514; DNA-dir_RNA_pol_30-40kDasu_CS.
DR InterPro; IPR011262; DNA-dir_RNA_pol_insert.
DR InterPro; IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR022842; RNAP_Rpo3/Rpb3/RPAC1.
DR InterPro; IPR033901; RNAPI/III_AC40.
DR InterPro; IPR036643; RNApol_insert_sf.
DR PANTHER; PTHR11800; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR11800:SF13; DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1; 1.
DR Pfam; PF01000; RNA_pol_A_bac; 1.
DR Pfam; PF01193; RNA_pol_L; 1.
DR SMART; SM00662; RPOLD; 1.
DR SUPFAM; SSF56553; Insert subdomain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF55257; RBP11-like subunits of RNA polymerase; 1.
DR PROSITE; PS00446; RNA_POL_D_30KD; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 51..329
FT /note="DNA-directed RNA polymerase RpoA/D/Rpb3-type"
FT /evidence="ECO:0000259|SMART:SM00662"
SQ SEQUENCE 335 AA; 37812 MW; D8739F01292E54B1 CRC64;
MSNLVNIEKD RVTNVSSTDF PGYDSNTDYA WDLQKFKDTL EIKVGYRTDR TLNFDLIHID
TSIANAFRRI MISEVPSVSV EHVYINNNSS VIQDEVLASR IGLVPLQIDP DRLSWVDRGV
EESERFTDEN TVVISLNVAC TKNPHPAKNN NDPENLYRNS IVYSRDLKFE PQGRQVETFA
DSPVVAADPD IVIAKLRPGQ EISLKAHCIL GLGSDHAKFS PVCTASYRLL PVINITQPIT
GKDAEKFQKC FPKGVIAIEN GQAVVKDARR DTVSRECLRH PEFEGKVKLA RQRDHFIFNV
ESTGCMPPEE IFFKSVRILK NKAEYLKNCP IGNMN
//
