ID   C4R9E9_KOMPG            Unreviewed;       505 AA.
AC   C4R9E9;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=triacylglycerol lipase {ECO:0000256|ARBA:ARBA00013279};
DE            EC=3.1.1.3 {ECO:0000256|ARBA:ARBA00013279};
GN   OrderedLocusNames=PAS_c034_0027 {ECO:0000313|EMBL:CAY67044.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY67044.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY67044.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
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DR   EMBL; FN392323; CAY67044.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4R9E9; -.
DR   InParanoid; C4R9E9; -.
DR   Proteomes; UP000000314; Chromosome 1, Contig 34.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00519; Lipase_3; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   PANTHER; PTHR46640:SF3; LIPASE LIH1-RELATED; 1.
DR   PANTHER; PTHR46640; TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..505
FT                   /note="triacylglycerol lipase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009950956"
FT   DOMAIN          272..399
FT                   /note="Fungal lipase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01764"
SQ   SEQUENCE   505 AA;  57821 MW;  C7A28627E354606A CRC64;
     MKSKWGILLT VVVTEICNYA AGLPTYNQTE VENFESFEER HADLSALYTA GRFARDLLSF
     GGIDPKAKLN YVLESSEQIN DDLFYQLATQ YIPLLQVAYC DNEQGALRTH ENSEFLLPPK
     LRLPFQCNET LENSQRRFRL LKVFRIPPHK MISKGGGNGY ILLDHKLKKI NVFFRGSRFA
     NDWLTNLDYV EKPYRPNVWN SSVVSETINN HDGVSENLIQ KYISRAVEVD SFTCNEWRNE
     TTERAPTIKY YQEIATLLHD SNRAEINSAF ERKTGGELCF NCEIHSGFNS VMKVVLPEIL
     PLVFQSIEQF PAYQLVLGGH SQGGAFAQIL QLELSLLQIK SFALTASASR VFSHELAYLY
     DLMTKVNEIE EHLIEGQFPT EGHVRIVHHG DIIPSIPFRN VFSHTGYEVY LANVYIPHST
     GDFYLSGMRE YLDILQDLDS SGIVESFRFS RGWVSFDYYL RKLGKLLKIK PTLKAIKDYV
     MNEKIGAYSH RNIIDNISAC NALRL
//