ID C4RG50_MICS3 Unreviewed; 897 AA.
AC C4RG50;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Two-component system response regulator {ECO:0000313|EMBL:EEP72292.1};
GN ORFNames=MCAG_02618 {ECO:0000313|EMBL:EEP72292.1};
OS Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=219305 {ECO:0000313|EMBL:EEP72292.1, ECO:0000313|Proteomes:UP000010307};
RN [1] {ECO:0000313|Proteomes:UP000010307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39149 / NRRL 15099 / SCC 1413
RC {ECO:0000313|Proteomes:UP000010307};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Galagan J., Nusbaum C., Birren B.;
RT "The genome sequence of Micromonospora carbonacea var. africana strain ATCC
RT 39149.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG657738; EEP72292.1; -; Genomic_DNA.
DR AlphaFoldDB; C4RG50; -.
DR STRING; 219305.MCAG_02618; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG0467; Bacteria.
DR HOGENOM; CLU_004665_2_1_11; -.
DR Proteomes; UP000010307; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 2.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010307};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 224..381
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REPEAT 688..721
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 768..801
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 154..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 854..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 897 AA; 96885 MW; 73555675ED25ABF2 CRC64;
MRPARSDDGS PQPSQKTSNI LHALIDLSGA ERCGRMSEAG GDAQQASAWF AGELRHLRQL
CGAPSLNTLV AISTAQGQPL ARSTISDKLN AKSLPDWPFV VAFVKACLAH ADRAGVRLPA
ELAEMRHWDA RHWRLLRIAD AARTEDRLRA AAHAQLGRRS GGAAPASQPE PPAPGPSPTG
QRAGVLDRVT PRQLPTAVPH FVGRRAALTR LDGLLAHRHR APGTTTICLI SGTAGVGKTS
LAVGWAHQVA DRFPDGQLYV NLRGFDATGP AASPAEVLRE FLEALGVPAQ RVPAGQDARS
GLFRSVLTGR RVLVLLDNAG DVDQVRPLLP GSPGCLVVVT SRGHLPGLVT IEGASPIFLD
PLSRREAHEL LSRRLGTDRL ENEPEATSRI VDAAAGLPLA LAIVAGRAAV QPALGLGRLA
DELTGSDGLD RFSHGDAATD IRTVFSWSYR NLDATSARAF RLLGLHPGPD VSVPALASLV
GAPVAEAGRT LAALVRANLV SEHLPQRYVL HDLLRAYAAE LVAEHEPEQA RRQALGRLID
SYLHTGYAAD LLLYDQRDPI SPAPARPGTA ITALTDRAAA WRWFTSEHRV LLAVVGLATD
ARFDTPAWQL AWAVNTYLDR LGAWQEQLVV QERALLAASR VADRDGQARA HRNRAVACLR
LGDHHQAQVH LRRSLRLYTG LGDAIGSARA HLNLGILAER LGRYEQALQH AQQALGLFAA
AENANGKANA LNNIGWYHSQ LGNHQQAIDY CTQALVLQRQ VGNRYWQAHT WDSLGYAHHR
LEQQAEAIRC YRNALALWRE AAERYYEATT LTHLGDTHRA AGAPGPARRA WRRALEILEL
LGHPDAEQLR DRLRAEPGGF PDQRAEARSG RATASSTATA VGESPSGRVR WSGRGGR
//
