ID   C4RI19_MICS3            Unreviewed;       134 AA.
AC   C4RI19;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:EEP70459.1};
GN   ORFNames=MCAG_00786 {ECO:0000313|EMBL:EEP70459.1};
OS   Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=219305 {ECO:0000313|EMBL:EEP70459.1, ECO:0000313|Proteomes:UP000010307};
RN   [1] {ECO:0000313|Proteomes:UP000010307}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39149 / NRRL 15099 / SCC 1413
RC   {ECO:0000313|Proteomes:UP000010307};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA   Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA   Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA   Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Galagan J., Nusbaum C., Birren B.;
RT   "The genome sequence of Micromonospora carbonacea var. africana strain ATCC
RT   39149.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG657738; EEP70459.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4RI19; -.
DR   STRING; 219305.MCAG_00786; -.
DR   eggNOG; COG1309; Bacteria.
DR   HOGENOM; CLU_069356_15_10_11; -.
DR   Proteomes; UP000010307; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR039538; BetI_C.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR   Pfam; PF13977; TetR_C_6; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010307};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          8..68
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        31..50
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   134 AA;  14367 MW;  5D72AB96A279C8DD CRC64;
     MARTRDLAQQ QAALSSATWA VLAERGIAGL TVRAVAERVG CTSGLVFHTF PSKQALLAHA
     RQTLFERAAA RVDAVERQGG TPAEVLENVM LTLLALDRDG AEEARVWISF LAAAPASPEL
     ADHHLAGNRP WCRA
//