ID C4RLJ9_MICS3 Unreviewed; 535 AA.
AC C4RLJ9;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Error-prone DNA polymerase {ECO:0000313|EMBL:EEP70908.1};
DE Flags: Fragment;
GN ORFNames=MCAG_01235 {ECO:0000313|EMBL:EEP70908.1};
OS Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=219305 {ECO:0000313|EMBL:EEP70908.1, ECO:0000313|Proteomes:UP000010307};
RN [1] {ECO:0000313|Proteomes:UP000010307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39149 / NRRL 15099 / SCC 1413
RC {ECO:0000313|Proteomes:UP000010307};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Kodira C.D., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I.,
RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D.,
RA Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C.,
RA Sykes S.N., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Galagan J., Nusbaum C., Birren B.;
RT "The genome sequence of Micromonospora carbonacea var. africana strain ATCC
RT 39149.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG657738; EEP70908.1; -; Genomic_DNA.
DR AlphaFoldDB; C4RLJ9; -.
DR STRING; 219305.MCAG_01235; -.
DR eggNOG; COG0587; Bacteria.
DR HOGENOM; CLU_001600_4_4_11; -.
DR Proteomes; UP000010307; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR InterPro; IPR040982; DNA_pol3_finger.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR NCBIfam; TIGR00594; polc; 1.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR PANTHER; PTHR32294:SF4; ERROR-PRONE DNA POLYMERASE; 1.
DR Pfam; PF07733; DNA_pol3_alpha; 1.
DR Pfam; PF17657; DNA_pol3_finger; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000010307};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..255
FT /note="Bacterial DNA polymerase III alpha subunit NTPase"
FT /evidence="ECO:0000259|Pfam:PF07733"
FT DOMAIN 258..420
FT /note="DNA polymerase III alpha subunit finger"
FT /evidence="ECO:0000259|Pfam:PF17657"
FT REGION 513..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 535
FT /evidence="ECO:0000313|EMBL:EEP70908.1"
SQ SEQUENCE 535 AA; 59641 MW; 450172D4D03A6288 CRC64;
MPAGHTEMSW LRALTMAGAR ERYGPPEAHP EAYRQLDHEL RMIDELGFPG YFLVVYDIVA
FCRRADIYCQ GRGSAANSAV CYALRITNVD AVRHRLLFER FLAPERDGPP DIDVDIESDR
REEVIQHVYA RYGREHAAQV ANVVSYRPRS AVRDVAKAFG FSPGQQDAWS RQIDRWGSVA
SVDAEDIPEQ VVAYADQLQT FPRHLGIHSG GMVICDRPVI EVCPVEWGRM PGRSVLQWDK
DDCAAVGLVK FDLLGLGMLS ALHYGYDMIG TTLDLGDMTL DDPEVYDMLC RADSVGVFQV
ESRAQMATLP RLKPREFYDL VVEVALIRPG PIQGGSVHPY IRRRNGQEPV TYPHPLMRNA
LEKTLGVPLF QEQLMQLAID LAGFDAAGAD QLRRAMGAKR SVQRMARVAD RLYAGMAERG
ITGELADDVY RKLTAFASYG FPESHAMSFA YLVYASSWLK RYHPGPFLAA LLGAQPMGFY
SPQTLVDDAR RHGVEVRRPD VNASGAKAVL ESTPDTRWAA RPASRRTPGG WAGRP
//
