ID C4XWC6_CLAL4 Unreviewed; 451 AA.
AC C4XWC6;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA damage checkpoint control protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CLUG_00249 {ECO:0000313|EMBL:EEQ36126.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ36126.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ36126.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ36126.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the rad1 family.
CC {ECO:0000256|ARBA:ARBA00010991}.
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DR EMBL; CH408076; EEQ36126.1; -; Genomic_DNA.
DR RefSeq; XP_002619090.1; XM_002619044.1.
DR AlphaFoldDB; C4XWC6; -.
DR STRING; 306902.C4XWC6; -.
DR GeneID; 8499902; -.
DR KEGG; clu:CLUG_00249; -.
DR VEuPathDB; FungiDB:CLUG_00249; -.
DR HOGENOM; CLU_038605_0_0_1; -.
DR InParanoid; C4XWC6; -.
DR OMA; IQFEVIL; -.
DR OrthoDB; 2048785at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:InterPro.
DR Gene3D; 3.70.10.10; -; 1.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR003021; Rad1_Rec1_Rad17.
DR PANTHER; PTHR10870; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR PANTHER; PTHR10870:SF0; CELL CYCLE CHECKPOINT PROTEIN RAD1; 1.
DR Pfam; PF02144; Rad1; 1.
DR PRINTS; PR01245; RAD1REC1.
DR SUPFAM; SSF55979; DNA clamp; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 49799 MW; 8F8F34FD06411816 CRC64;
MSQLFIPSSP DQKSPPPSSQ YVDSNLKFSA STIQVAHMAE ILGAITSIHH QALIIINDSG
ITLYSEYNHI LNAQLTIDAS FFSVFEITGG EDTSGSNREL RLGVDVSLIS DSFAAAASTA
SAPRGKYGNG SSTETVVCYM KYEGEGSPLI IEFEDRLMSE QIEFATFFIE TEYPYDTLTS
QQKAEDHVLL IDRDLIQFEV ILKGDLLSNL LQDLQNLNTQ ELYMQVSNQA KRGTVTQHNE
LNFISKGSIG YSKLIFPNGK TMLEKLEIFQ QENGKVVPIK STVLSCFNFS PLAKTLRAVK
MSSKCKIMKD SSGVLSLQLL CKKPTSSNYP GTLITFNMLE TAVNTNDVGQ QVNVDVDDIF
DDQLYRYIKQ VEPSGSRAEI ESRIPDSDEN AVVELSADSR QPFSYASFKR PRISHGPEEG
TSKSRKPEIQ DDELAGDVTT VGGAIEIPLF L
//
