ID C4Y405_CLAL4 Unreviewed; 500 AA.
AC C4Y405;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS00028};
GN ORFNames=CLUG_02377 {ECO:0000313|EMBL:EEQ38251.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ38251.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ38251.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ38251.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH408078; EEQ38251.1; -; Genomic_DNA.
DR RefSeq; XP_002616933.1; XM_002616887.1.
DR AlphaFoldDB; C4Y405; -.
DR STRING; 306902.C4Y405; -.
DR GeneID; 8497558; -.
DR KEGG; clu:CLUG_02377; -.
DR VEuPathDB; FungiDB:CLUG_02377; -.
DR HOGENOM; CLU_027160_1_0_1; -.
DR InParanoid; C4Y405; -.
DR OMA; IPHWLYK; -.
DR OrthoDB; 5483967at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR031590; PRP9_N.
DR InterPro; IPR024598; SF3a60/Prp9_C.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR12786:SF2; SPLICING FACTOR 3A SUBUNIT 3; 1.
DR PANTHER; PTHR12786; SPLICING FACTOR SF3A-RELATED; 1.
DR Pfam; PF16958; PRP9_N; 1.
DR Pfam; PF11931; SF3a60_Prp9_C; 1.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 267..289
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 349..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..376
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 57501 MW; 0755C530EA5F111C CRC64;
MNLAETQRQT LEEIDILEVE TAQRFRRNPE LGRAAQIRQT DSVLESRRKR PHKETLLQQH
ELKYFSNQYE RDCSRAIKNF ESPELLSQIE SLRDPNLKFE SINRALTELE SRFKSVPIQS
ATPSRSAFLM YSSAPEDGVK TVGSKKKFKR RYFLSSATSY LAQEVGESFG DLEMYGKVLG
LQAYYEIYRS LFPSKLTYAE YLRSFSKFPN SNNSTDYLRY LESLLNYLKK MHVQCFPLKA
LPELGKTRSK ATEIEDGERN EQGEIFCKAC DKYFAKESVY KGHLDGKKHK KNSLKQTTTS
KVNSVTAQDL ERDIEEMTKA MGPLLDATIS DYERRSAFSD REKMLETLAV EGEESEFTAE
DSTSEASEDN DDDDEFYSKD MPIGTDGTPI PLWLYKLQGL HRTYKCEICG NTSYKGRQQF
TKHFTQSKHI RGLMCLGIGE METPLFNSIS SIAEAQALWK QFKKAKSAEE EDLDNVEIED
SEGNVMSHKD YVELKKQGLL
//
