ID C4Y6X3_CLAL4 Unreviewed; 2548 AA.
AC C4Y6X3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEQ39779.1};
GN ORFNames=CLUG_03907 {ECO:0000313|EMBL:EEQ39779.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ39779.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ39779.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ39779.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CH408079; EEQ39779.1; -; Genomic_DNA.
DR RefSeq; XP_002616666.1; XM_002616620.1.
DR STRING; 306902.C4Y6X3; -.
DR GeneID; 8496989; -.
DR KEGG; clu:CLUG_03907; -.
DR VEuPathDB; FungiDB:CLUG_03907; -.
DR HOGENOM; CLU_000740_0_0_1; -.
DR InParanoid; C4Y6X3; -.
DR OMA; PNYFAKP; -.
DR OrthoDB; 607689at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR019439; FMP27/BLTP2_N.
DR InterPro; IPR019409; FMP27_sixth_RBG.
DR InterPro; IPR019415; FMP27_SW_RBG.
DR InterPro; IPR019449; FMP27_WPPW_RBG.
DR InterPro; IPR045167; Hobbit.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF10293; DUF2405; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10344; FMP27-BLTP2_N; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF10305; Fmp27_SW; 1.
DR Pfam; PF10359; Fmp27_WPPW; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
DR SMART; SM01215; Fmp27_SW; 1.
DR SMART; SM01216; Fmp27_WPPW; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1116..1217
FT /note="FMP27 SW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01215"
FT DOMAIN 1235..1392
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
FT DOMAIN 1643..2069
FT /note="FMP27 WPPW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01216"
FT REGION 236..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2395..2424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1821..1848
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 471..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2409..2424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2548 AA; 291040 MW; 44ED93A9A889EA08 CRC64;
MYPLSSWGCH ALLALIGLRL FWLLAFRIFG LYLGYISINN GISFNEVYWY TKHRKISASS
VRFRLWGNSK KIIIADLKVQ LYSQPKGKPR QPKRFISSEP CTIYPENKLA VYLYRFVLRL
LPSANIDIKR GQLETKNENI SFAQLQFVFI KHRSAHEPNV YRFDAMSSIY QASGKLHSSG
SSIPMSSGCC GLKASCSISA TTGKVSHFTA HIQVDDSEID VLHAIKGSIF RANKATDANE
SSTNSAKDRQ VIESESKTHT TLEGHLETFS SIHKKYFGAF QECSISIRNT HFKGFPLFPA
NDTQDLTDYL SKDDVDISVS VSVSTIAFNI ARITSKSAGY DVLFDATTDK PLEVNTSVSI
LKAFFVSKHY DNSGEKAYYK KDEILDIPNY SLALKTNITD RFANGYGFEK AVSELIFSCG
SPVIDVTADQ FALLTYNYVV AKKLFTLGHL KKQNAASRFD TFKNTESDSE LDGDTQVAAS
EPSTPQVVKS KFTDSPQLKE LKVDLSPSSF ESFETSKPRD EFTLRKSEIV FNSPFNKIMA
LINEFYPRLD VKFTMEQPRV MIRSLNADKS TTKMLMISYS MIVLHIATTL DNTYVATCNL
LHPCITFSER FGCHQHVEDF CGLSDLTINC NISRDFKVTT SLNIQGVYMN LTKPDVLNGI
SHIIEETTRI VNQNLTSGLI NKRFDAEIVQ ELDLGTKGQR RTQTPHKDDS LDIIFSDCPM
WFVSATLKVT DVDLRLGSIS PLLPPELISK LSQESQFNEK FVGTNSILNL SIDEIIFALR
SVPEVSGSDS MLAVSSSETL SNDVNDHIFW QIESTIRNNK ICLLENQKRQ QPIMYLPQLS
VLIQSAIKGQ QKVVDSSVEV DEVLGHIDRH SIFVIIGSVY LVHQTIVTPI NQLCNKLRRN
MESLHRNDSK TKRLFISEFL SFKVSLPKFN YVFSLSDEFK LYLQLFQLNI GGQDSGITLS
SNFFRLLVNS TEVKGHWNRL LCADYLQFKV NDLMGIPSFL FDANSIRIIQ PHQFAVYRLF
DNLAVFTKVI KHLLKSMKLE EKSQIVSPKE SPPLNIPVIN IKAKQIFFSI EDDPFEAELG
MIYQLGLQEQ KKRLEMMDVL YGKARTQYTS EESLSQKITE IQKIMEGSWI RKVKAYKSRI
AQEIIDNQDF LFGAEVHIKE DKCHNILPYS RTAPLCHMIL SGVDLDLSSI NFPFDDIPRF
VHDKGQGVPG DTKYNLVIPA YVDLCVRELR IHARDYPLPL LNLPDSMDSR GKGNSLKLKG
NLIINEALSL EEEHIRRLEV QLTKASSGSQ PNSFDKLIIR KSMSTVKFYT DLDIMFGSKS
PSRFVWGQSY SFVIQQIMAS LDQFSKPPVD PSPKLGFWDK FRYIFHGNCA VKTSGDACIE
FAFKGDRDPY NLFEKASGFV LSFRDRVKWN VNSNDDSLQF CKVNSNKVLW YIPNYLSAPL
VCWSRESHKS TYLPELNQLV TSCFGYYLNP QKRNGKINEE KSVHNVCAKR VVELSGGVDF
TLGFLLQRHA SESGTISSDG KLHWEINLNN PAYVKEGHDS YKGFRTDRVH MAITLVAHTQ
SSYNTIHLSP GVFQQFFAWW SLFKSNMMLQ VRRGKLFPNS KKSTKFSEHL FTNKFLFHIR
DLFLSHIYDD SGYDVDDKVK FIGMRAKVSE FLVDLHQRKE ERIDAHKDLS RHKKIMKMNF
NQAEVALSKI DLRMMCTEYF KDIYEHNDDL AETETQKSKC EYTIFDKDYQ WFDDKDYVEA
FAPLSGRKRE KMAAFPFMYS ERFAFIRQTK SPDNIDWGAE HTHDCMLGST DVEATGLNMF
EARISELQKL NESSDTSYED SHQVKREIEA LQQMKSNLKK EKRSFLKSST IEFEQHQNEN
FNNKFVLISM LLKWNESVRN LFLRYIYFVE FRSNMQKYLS YEFITMLEGL IDRKNSNDAN
SSLLSSVTDG VPNVEKLRSF LNEFSTSQDR IVNFDKIIRK VSEDETFEES FKIEVINPQI
QLHSETVDNS VVLVTAPVLE SKILTINSKK EDSLVTYSKE LETRFGILLH DESVLVVDKR
AVKAQKAPWA IKSYGSKSAW PPFLGIEICK NNSLAQDNIV LVRRMSMMLT YDKVKASNSN
IDQIEVASAG SAEDIFAEGM DRLRVDVPKL EINCTSSQYF SLYVTILSLI LYSEPRSARM
AEKLRQLKFT IDFQDFSALH DRLVSLHAYL DVVNTIINNY SFRHSTRMSN EELNDYILLR
NEKTENSAEI YLMLKTLLTG DIFADTSAQP IEDWRIAADR IILNILTDER KPILNLSINN
GRYKRVTKED GSNHNRVEIK SLEGRSLVEG AYYDKFLEPS YPPDGNDLVA VEWSMKRPIG
GIKIINNFNI SSQPLNVKLD EKTGMQLMNF IFHMENSSDY SDSPVSKAID IIPNNKEHAG
EGSGDSDEDS DEERKKVRFR DGSSSMTKKK TLSFISGSET NTEVGHDVNE MISRSKKYLS
VVSFVCQSFE LTISLKMKHG FKRWLNVNQF TLILPEWQIE RTVTSMLGVV DVFKKLVIKT
LLSSSGSLLA NKMRSRSAND RKRLKKGR
//
