ID C4Y9H2_CLAL4 Unreviewed; 274 AA.
AC C4Y9H2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 22-FEB-2023, entry version 47.
DE RecName: Full=Uroporphyrinogen decarboxylase (URO-D) domain-containing protein {ECO:0000259|PROSITE:PS00907};
GN ORFNames=CLUG_04862 {ECO:0000313|EMBL:EEQ40733.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ40733.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ40733.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ40733.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408081; EEQ40733.1; -; Genomic_DNA.
DR RefSeq; XP_002614846.1; XM_002614800.1.
DR AlphaFoldDB; C4Y9H2; -.
DR STRING; 306902.C4Y9H2; -.
DR GeneID; 8495720; -.
DR KEGG; clu:CLUG_04862; -.
DR VEuPathDB; FungiDB:CLUG_04862; -.
DR HOGENOM; CLU_040933_0_0_1; -.
DR InParanoid; C4Y9H2; -.
DR OMA; LWLMRQA; -.
DR OrthoDB; 34606at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR PANTHER; PTHR21091; METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED; 1.
DR PANTHER; PTHR21091:SF169; UROPORPHYRINOGEN DECARBOXYLASE; 1.
DR Pfam; PF01208; URO-D; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
DR PROSITE; PS00907; UROD_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007703}.
FT DOMAIN 59..75
FT /note="Uroporphyrinogen decarboxylase (URO-D)"
FT /evidence="ECO:0000259|PROSITE:PS00907"
SQ SEQUENCE 274 AA; 30958 MW; AA969CB0D1D998BC CRC64;
MGFEIEMIEG KGPVFVDPLR SPADLSRVQM KPDILTSLDW AFKAITLTRT KLNGRVPLLG
FCGAPWTLLV YMTEGQGSKM FRFAKQWLYE YTQESHKLLQ AITDACIEFL AQQVVAGAQM
LQVFESWAGE LGPHEFAEFC LPYLRQIASK LPLRLKELGV EEKIPLTVFA KGAWYALDDL
CESGYDTVSL DWLYKPEDAV KVVGSRRITL QGNLDPGIMY GTDEVITQKV EQMIKGFGGG
KQNYIINFGH GTHPFMKPEK IEHFLKECHR IGSQ
//
