ID C4YCK7_CLAL4 Unreviewed; 358 AA.
AC C4YCK7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CLUG_05935 {ECO:0000313|EMBL:EEQ41807.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ41807.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ41807.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ41807.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CH408083; EEQ41807.1; -; Genomic_DNA.
DR RefSeq; XP_002614449.1; XM_002614403.1.
DR AlphaFoldDB; C4YCK7; -.
DR STRING; 306902.C4YCK7; -.
DR GeneID; 8494709; -.
DR KEGG; clu:CLUG_05935; -.
DR VEuPathDB; FungiDB:CLUG_05935; -.
DR HOGENOM; CLU_014015_6_0_1; -.
DR InParanoid; C4YCK7; -.
DR OMA; TRANDVF; -.
DR OrthoDB; 5770at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 358 AA; 40408 MW; C6069F454B55896E CRC64;
MLLDIDRVIS TDKQDSISSN VLAPYSYLAQ LAGNNNNMRY RFLVAFNMRF FKIDNTQVLS
EIGDIIAIFH NASLLIDDIE DSSELRRGHP CAHTKYGVPL TINSGNLMYF VALQRAITAL
PNLWLELQEQ KGIGYGQSGT DLTVVNPSVI ECKTNRILVD EMLNLHQGQG LDIYWRDSLH
EIMENLPTIE EYLSMVMNKT GGLFRLSVKL LALFSPSPLQ VETLIPLANL LGIIYQIRDD
YLNLIDERYF GMKGVAGEDL IEGKLSLPVL HCLLHNEEKS ALHYVLLDLK TSEDRKNDPD
SIAKAILFIK ESGSLKFTYD LLQEYVSKAL QMLGSFPEPD DACKLREIVV SFSNVMEP
//
