ID C4Z976_AGARV Unreviewed; 610 AA.
AC C4Z976;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:ACR75298.1};
GN OrderedLocusNames=EUBREC_1554 {ECO:0000313|EMBL:ACR75298.1};
OS Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835
OS / VPI 0990) (Eubacterium rectale).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Agathobacter.
OX NCBI_TaxID=515619 {ECO:0000313|EMBL:ACR75298.1, ECO:0000313|Proteomes:UP000001477};
RN [1] {ECO:0000313|EMBL:ACR75298.1, ECO:0000313|Proteomes:UP000001477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / LMG 30912 / VPI
RC 0990 {ECO:0000313|Proteomes:UP000001477};
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC -!- PATHWAY: Cell wall biogenesis; lipoteichoic acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004936}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001107; ACR75298.1; -; Genomic_DNA.
DR RefSeq; WP_012742397.1; NC_012781.1.
DR AlphaFoldDB; C4Z976; -.
DR STRING; 515619.EUBREC_1554; -.
DR PaxDb; 515619-EUBREC_1554; -.
DR KEGG; ere:EUBREC_1554; -.
DR HOGENOM; CLU_014385_1_0_9; -.
DR Proteomes; UP000001477; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 242..538
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT REGION 570..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 69639 MW; 8F6754BF28210BFF CRC64;
MMIKKIYKKY EIIFNVIFFS IFPIMAFYLM EFYDHNPFEE VRFMAGFFNI ILFELIAWIL
YFVTGRAKWA LRAVFIVAMV FGLINHYVML FRSTPFVPWD IFSIGTATSV ASNYDFAPTA
GVVVVTVIFI ALIMLMHFVD FRIKWKFRLR LIPTVLGILA LCLFVNALQD EDFQTDNYLY
PFLFTPAYMT KVNGMAVTFA MDLKFVAVDK PDGYSRQKAK ELLDSYAGTD DNTAITDKSD
YPNIIVVMDE AFSDLSVLGG FDTNTDYMPF VHSLEKGNEN TITGYLNTSV CGGNTADTEF
EFLTGNTMAF LPVGSIPYQQ YIKSTTPSLA SYLKSIGYAT YAQHPYYGSG WNRDTVYPLL
GFDNLSFMQD YSNQRFVRKY ISDETSFDRI IETYENKPDG QPAFIFNVTM QNHGGYTDTY
YGFDNTVTAD KLNNSALDQY LSLIKLTDED LKSLIEYFSN VDEKTIVVFF GDHQPNDTVA
SSVLAANGMD YNNLSNEELK LRYQVPYVIW ANYDIDEAAG KDTSVNYLAA NVLKAAGVPT
NDYQSFLLKL QEEYPIISAV RTDKTADKTL DKASNKSDKA TGSKKKQADS DMLNDYKLLQ
YYRLFDWEDK
//
