ID C5A1Q2_THEGJ Unreviewed; 112 AA.
AC C5A1Q2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Murein hydrolase exporter, putative lrgA-like protein (LrgA) {ECO:0000313|EMBL:ACS34321.1};
GN Name=lrgA {ECO:0000313|EMBL:ACS34321.1};
GN OrderedLocusNames=TGAM_1819 {ECO:0000313|EMBL:ACS34321.1};
OS Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=593117 {ECO:0000313|EMBL:ACS34321.1, ECO:0000313|Proteomes:UP000001488};
RN [1] {ECO:0000313|EMBL:ACS34321.1, ECO:0000313|Proteomes:UP000001488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15229 / JCM 11827 / EJ3
RC {ECO:0000313|Proteomes:UP000001488};
RX PubMed=19558674; DOI=10.1186/gb-2009-10-6-r70;
RA Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M.,
RA Anthouard V., Forterre P., Wincker P., Confalonieri F.;
RT "Genome analysis and genome-wide proteomics of Thermococcus gammatolerans,
RT the most radioresistant organism known amongst the Archaea.";
RL Genome Biol. 10:R70.1-R70.23(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001398; ACS34321.1; -; Genomic_DNA.
DR RefSeq; WP_015859430.1; NC_012804.1.
DR AlphaFoldDB; C5A1Q2; -.
DR STRING; 593117.TGAM_1819; -.
DR TCDB; 1.E.14.1.5; the cida/lrga holin (cida/lrga holin) family.
DR PaxDb; 593117-TGAM_1819; -.
DR GeneID; 7987646; -.
DR KEGG; tga:TGAM_1819; -.
DR PATRIC; fig|593117.10.peg.1828; -.
DR eggNOG; arCOG03636; Archaea.
DR HOGENOM; CLU_113736_4_2_2; -.
DR OrthoDB; 85741at2157; -.
DR Proteomes; UP000001488; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR005538; LrgA/CidA.
DR PANTHER; PTHR33931:SF2; HOLIN-LIKE PROTEIN CIDA; 1.
DR PANTHER; PTHR33931; HOLIN-LIKE PROTEIN CIDA-RELATED; 1.
DR Pfam; PF03788; LrgA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:ACS34321.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 112 AA; 12217 MW; 8891592BD6256427 CRC64;
MRPYRGLTVI FGFYALGEIV SSGLHLPVPG SVLGMLFLLF ALLSGAVKLE WVENEAEFLV
KNMSVLFIPP GVGIILYLGL IRAQLVPVSV ALVLSFVITL FVTAKTVEVL RR
//
