ID C5ADH5_BURGB Unreviewed; 402 AA.
AC C5ADH5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Efflux pump membrane protein {ECO:0000313|EMBL:ACR30165.1};
GN OrderedLocusNames=bglu_1g31020 {ECO:0000313|EMBL:ACR30165.1};
OS Burkholderia glumae (strain BGR1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=626418 {ECO:0000313|EMBL:ACR30165.1, ECO:0000313|Proteomes:UP000002187};
RN [1] {ECO:0000313|EMBL:ACR30165.1, ECO:0000313|Proteomes:UP000002187}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGR1 {ECO:0000313|EMBL:ACR30165.1,
RC ECO:0000313|Proteomes:UP000002187};
RX PubMed=19329631; DOI=10.1128/JB.00349-09;
RA Lim J., Lee T.H., Nahm B.H., Choi Y.D., Kim M., Hwang I.;
RT "Complete genome sequence of Burkholderia glumae BGR1.";
RL J. Bacteriol. 191:3758-3759(2009).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001503; ACR30165.1; -; Genomic_DNA.
DR RefSeq; WP_015877019.1; NC_012724.2.
DR AlphaFoldDB; C5ADH5; -.
DR STRING; 626418.bglu_1g31020; -.
DR KEGG; bgl:bglu_1g31020; -.
DR PATRIC; fig|626418.3.peg.6037; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_0_4; -.
DR Proteomes; UP000002187; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR005694; MFP_proteobact.
DR NCBIfam; TIGR00998; 8a0101; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002187};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..289
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 290..344
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
SQ SEQUENCE 402 AA; 43093 MW; 057241F9844D655D CRC64;
MSDPQQQAAA PAARNDGKRK WLMTLLVVII VLAAIAYGIY YFLVARFHED TDDAYVNGNV
VQITPQVTGT VIAVNADDTQ SIREGEPLVQ LDPADARIAL QSAEAKLAQT VRRVRGLYAA
DDQYRAQVAQ RESDLSKAQD DLRRRLAVAQ TGAVSQEEIS HARDAVKAAQ ATLDAARQQL
AANLALTANT TVSHHPDVLA AVATVRDAYL ANARNTLPAP VTGYVAKRTV QVGQRVSPGT
PLMSVVPLGQ IWVDANFKEV QLDHMRIGQP VELTADIYGS SVTYHGKVAG FSAGTGSAFS
LLPAQNATGN WIKVVQRLPV RIALDPRELE RHPLRIGLSM QADVSIKDES GSQLGSVSNT
VYQTEVFAKY GDAANAEIAR IIAENAGGPV RAAQPAPRAP RA
//
