ID C5AR97_METEA Unreviewed; 315 AA.
AC C5AR97;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=Histidine-specific methyltransferase SAM-dependent domain-containing protein {ECO:0000259|Pfam:PF10017};
GN OrderedLocusNames=MexAM1_META1p2425 {ECO:0000313|EMBL:ACS40206.1};
OS Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB
OS 9133 / AM1) (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=272630 {ECO:0000313|EMBL:ACS40206.1, ECO:0000313|Proteomes:UP000009081};
RN [1] {ECO:0000313|EMBL:ACS40206.1, ECO:0000313|Proteomes:UP000009081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
RC {ECO:0000313|Proteomes:UP000009081};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
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DR EMBL; CP001510; ACS40206.1; -; Genomic_DNA.
DR RefSeq; WP_012752856.1; NC_012808.1.
DR AlphaFoldDB; C5AR97; -.
DR STRING; 272630.MexAM1_META1p2425; -.
DR KEGG; mea:Mex_1p2425; -.
DR eggNOG; COG4301; Bacteria.
DR HOGENOM; CLU_049766_1_1_5; -.
DR OrthoDB; 5289726at2; -.
DR Proteomes; UP000009081; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035094; EgtD.
DR InterPro; IPR019257; MeTrfase_dom.
DR InterPro; IPR017804; MeTrfase_EgtD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR03438; egtD_ergothio; 1.
DR PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR Pfam; PF10017; Methyltransf_33; 1.
DR PIRSF; PIRSF018005; UCP018005; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000009081};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 16..313
FT /note="Histidine-specific methyltransferase SAM-dependent"
FT /evidence="ECO:0000259|Pfam:PF10017"
SQ SEQUENCE 315 AA; 34137 MW; 883C7737958FB0E4 CRC64;
MSAAEAVASE RAEFLRDALA GLSGEAKTLP GKYLWDETGS DLFDRICAHP DYYPTKREMA
LLPRVAAEVA ALVGPGVSVV EFGSGASRKI RTLLDALEAP AAYLALDISG AYLEAAIARL
APDYPAVPMI PVCADYSKPI RLPPGAAAPP ILGFFPGTSI GNFTPEQAEG FLARARRTLG
PSHFLVGADP THDPARLRRA YGEAGGLMPA LHLNLIERMN RELGSNFDRS NFRHEARLAD
DPFRVEAHLV ATRPAAYRLG DRTIRFAGGE SIRTDTSHKY APDTFRALAS AQGWEPVRLW
VDEDSGFSLH LFRAP
//
